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Tag: Oncology

Adjuvant radiation may preserve HRQoL for low-risk breast cancer patients aged 70+

Cancer therapy, advanced medical linear accelerator in the therapeutic oncology to treat patients with cancer.

Two-year interim findings from the EUROPA trial indicate that radiotherapy after surgery for low-risk early breast cancer may be better for preserving health-related quality of life for women aged 70 years and older than endocrine therapy.

Primary MMR deficiency ‘underdiagnosed’ among young people with glioma

Cancer of the brain as tumor growth diagnosis and symptoms of gliomas meningiomas astrocytomas and oligodendrogliomas as diagnosis of symptoms as a paper sculpture.

Primary mismatch repair deficiency in gliomas is underdiagnosed among people younger than 40 years old, say investigators who recommend assessment of the biomarker to help facilitate checkpoint inhibitor therapy.

Polygenic risk score predicts Gleason upgrading during active surveillance

Kind smiling female doctor embracing encouraging happy senior male patient in hospital. Happy healthy older man and his physician enjoying talking at nursing home. Elderly medical health care concept.

A polygenic risk score may help to identify patients undergoing active surveillance for clinically localised prostate cancer who are at particular risk of an increase in their Gleason grade, US research shows.

Omitting axillary biopsy ‘noninferior’ for early-stage breast cancer survival

MultiCare Platinum Prone Breast Biopsy Table, Multicare Biopsy Table Mammography, Lorad, Prone table stereotactic breast biopsy

For women undergoing breast-conserving surgery for invasive breast cancer, omission of axillary sentinel lymph node biopsy offers noninferior 5-year invasive disease-free survival compared with standard axillary surgery, say the INSEMA trial investigators.

Hypofractionated proton beam therapy regimen feasible for glioblastoma in older patients

Patient Radiation proton therapy fixing mask showing laser lines for targeting cancer cells in the brain

A short course of hypofractionated proton beam therapy given alongside temozolomide may offer an improvement in overall survival for patients aged 65 years and older with a new diagnosis of glioblastoma, suggesting findings from a “hypothesis-generating” study.

Routine postoperative imaging may improve pancreatic cancer survival

Senior man going into CT scanner. CT scan technologist overlooking patient in Computed Tomography scanner during preparation for procedure

Research suggests that patients who are invited for routine imaging after pancreatic ductal adenocarcinoma resection have significantly longer overall survival than those who undergo imaging only after the development of symptoms.

Impact of haematological malignancy on pregnancy revealed

Women who are diagnosed with haematological malignancies during pregnancy have similar overall survival to peers diagnosed within a year of their pregnancy ending, indicates research published in The Lancet Haematology.

European retinoblastoma report shows stabilised incidence, high 5-year survival

Young child getting an eye exam at clinic.

The incidence of retinoblastoma in children in Europe stabilised between 2000 and 2013, say EUROCARE-6 Working Group investigators who report high 5-year survival rates in this population.

Fear of recurrence persists for decades among paediatric cancer survivors

Sad sick girl with pink headscarf hugging plush toy in the hospital

A third of adults who survive childhood cancer continue to have a fear of cancer recurrence for decades after their diagnosis, highlights research published in JAMA Network Open.

First-line trabectedin use boosts OS for advanced leiomyosarcoma

Doctor's gloved hand controlling perfusion offering cancer treatment

LMS-04 trial findings show a significant overall survival benefit with the use of induction and maintenance trabectedin alongside first-line doxorubicin for patients with inoperable, advanced leiomyosarcoma.

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