Hypofractionated proton beam therapy regimen feasible for glioblastoma in older patients
A short course of hypofractionated proton beam therapy given alongside temozolomide may offer an improvement in overall survival for patients aged 65 years and older with a new diagnosis of glioblastoma, suggesting findings from a “hypothesis-generating” study.
Routine postoperative imaging may improve pancreatic cancer survival
Research suggests that patients who are invited for routine imaging after pancreatic ductal adenocarcinoma resection have significantly longer overall survival than those who undergo imaging only after the development of symptoms.
Impact of haematological malignancy on pregnancy revealed
Women who are diagnosed with haematological malignancies during pregnancy have similar overall survival to peers diagnosed within a year of their pregnancy ending, indicates research published in The Lancet Haematology.
European retinoblastoma report shows stabilised incidence, high 5-year survival
The incidence of retinoblastoma in children in Europe stabilised between 2000 and 2013, say EUROCARE-6 Working Group investigators who report high 5-year survival rates in this population.
Fear of recurrence persists for decades among paediatric cancer survivors
A third of adults who survive childhood cancer continue to have a fear of cancer recurrence for decades after their diagnosis, highlights research published in JAMA Network Open.
First-line trabectedin use boosts OS for advanced leiomyosarcoma
LMS-04 trial findings show a significant overall survival benefit with the use of induction and maintenance trabectedin alongside first-line doxorubicin for patients with inoperable, advanced leiomyosarcoma.
Annual screening supported for people at high-risk of pancreatic ductal adenocarcinoma
Findings from the Cancer of the Pancreas Screening program in the USA support the use of annual endoscopic ultrasound or magnetic resonance imaging for patients with a familial or genetic predisposition for pancreatic ductal adenocarcinoma.
Surveillance effective for childhood cancer predisposition syndrome management
Early detection of tumours in children with a cancer predisposition syndrome can be achieved with standardised surveillance protocols, US cohort study findings demonstrate.
Phoenix Sepsis Score ‘accurate’ for children undergoing cancer treatment
The Phoenix Sepsis Score “accurately” characterises the risk of definitely attributable mortality from sepsis and the duration of intensive care unit stay in children undergoing cancer treatment who have a suspected infection, US researchers report.
Pharmacogenomic-guided induction therapy might reduce pediatric AML racial disparities
Using a pharmacogenomic strategy to guide choice of induction therapy for acute myeloid leukaemia might help overcome the disparity in outcomes between Black and White children, suggests research published in JAMA Network Open.
