Raised neutrophil count linked to amyotrophic lateral sclerosis onset
Increased neutrophil levels may be associated with an increased risk of developing amyotrophic lateral sclerosis, say researchers.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Intra-arterial chemotherapy approach shows promise for advanced unilateral retinoblastoma
The likelihood of successful globe salvage for children with advanced unilateral retinoblastoma is higher with intra-arterial chemotherapy than with a conventional intravenous approach, randomised trial findings suggest.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Base-edited CAR T-cell therapy shows promise for relapsed, refractory childhood ALL
Base-edited chimeric antigen receptor T-cell therapy is feasible for the treatment of relapsed or refractory childhood T-cell acute lymphoblastic leukemia, suggests research published in The New England Journal of Medicine.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Brain imaging aids long-term outcome prediction in paediatric cardiac arrest
Research suggests that magnetic resonance imaging and magnetic resonance spectroscopy conducted within 2 weeks of a cardiac arrest may help determine longer-term outcomes in children.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Add-on tofacitinib shows treatment promise in SSc-ILD
The addition of tofacitinib to conventional disease-modifying antirheumatic drugs could help alleviate sclerosis in patients with systemic sclerosis-associated interstitial lung disease, suggests research.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Cortical gyrification a possible early biomarker for PD progression
Researchers have found reductions in cortical gyrifications in patients with newly diagnosed Parkinson’s disease that worsen over time and may therefore serve as a potential biomarker for disease progression.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Early surgery improves survival for children with drug-resistant epilepsy
Study findings highlight the importance of a multidisciplinary comprehensive approach to drug-resistant epilepsy in children, with the consideration of both medical and surgical treatment options.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Pathogenic variants have additive effect on ALS survival
Genetic variants that modify survival in amyotrophic lateral sclerosis (ALS) can act on their own or in unison, having an additive effect and significantly worsening a patient’s outcome, researchers report in the journal Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Glucocorticoid withdrawal prevalent and persistent after hypercortisolism surgery
Myalgias and arthralgias are prominent symptoms associated with glucocorticoid withdrawal syndrome following surgical remission of endogenous hypercortisolism, report Irina Bancos, from the Mayo Clinic in Rochester, Minnesota, USA, and colleagues.
Urinary DKK3 signals declining kidney function and treatment response in children
Increased urinary Dickkopf-related protein 3 levels could indicate declining kidney function in children with chronic kidney disease and be a marker of treatment response, report researchers in The Lancet Child and Adolescent Health.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
