Haplo-SCT plus dinutuximab beta ‘feasible’ for relapsed high-risk neuroblastoma
Children with relapsed, high-risk neuroblastoma may benefit from immunotherapy with dinutuximab beta after haploidentical stem-cell transplantation, investigators write in the Journal of Clinical Oncology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Physical frailty identified as possible target in Parkinson’s disease prevention
Physical frailty may be a risk factor for Parkinson’s disease, particularly in people with a high genetic risk for the condition, suggest study findings published in JAMA Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Baricitinib disappoints in SLE-BRAVE trials
Baricitinib has achieved largely negative results in the SLE-BRAVE trials, published in The Lancet.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Promising results for focused ultrasound ablation in Parkinson’s disease
Focused ultrasound ablation of the globus pallidus internus improved symptoms in a substantial proportion of people with Parkinson’s disease in a randomised trial, but it comes with side effects.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Mild gestational glucose intolerance tied to future type 2 diabetes risk
Impaired glucose tolerance during pregnancy that does not meet the criteria for gestational diabetes nevertheless increases the likelihood that women will later develop type 2 diabetes, a study shows.
Age-specific CS differences may complicate diagnosis in older patients
Older adults with Cushing’s syndrome are less likely than younger patients to present with typical symptoms of cortisol excess, report Elena Valass and co-researchers.
LAMP2: Atropine eyedrops may reduce myopia incidence in children
Children using nightly atropine eyedrops have a significantly lower incidence of myopia during 2 years of use than those using placebo, show the findings of the LAMP2 randomised trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Reflux symptoms predict interstitial lung disease progression in SSc
Post-hoc analysis of a randomised trial shows that the severity of reflux symptoms in patients with systemic sclerosis predicts radiographic progression of interstitial lung disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Anthracycline heart failure risk quantified for breast cancer, lymphoma patients
Patients who receive an anthracycline during treatment for breast cancer or lymphoma are more than three times as likely to develop congestive heart failure than healthy individuals, indicates a case–control study published in JAMA Network Open.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Health informatics system aids timely, equitable diabetes care
A health informatics system based on routine clinical data helps physicians to prioritize high-risk people with diabetes, deliver more equitable care, and manage healthcare capacity, report researchers.
