Brain imaging aids long-term outcome prediction in paediatric cardiac arrest
Research suggests that magnetic resonance imaging and magnetic resonance spectroscopy conducted within 2 weeks of a cardiac arrest may help determine longer-term outcomes in children.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Add-on tofacitinib shows treatment promise in SSc-ILD
The addition of tofacitinib to conventional disease-modifying antirheumatic drugs could help alleviate sclerosis in patients with systemic sclerosis-associated interstitial lung disease, suggests research.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Cortical gyrification a possible early biomarker for PD progression
Researchers have found reductions in cortical gyrifications in patients with newly diagnosed Parkinson’s disease that worsen over time and may therefore serve as a potential biomarker for disease progression.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Early surgery improves survival for children with drug-resistant epilepsy
Study findings highlight the importance of a multidisciplinary comprehensive approach to drug-resistant epilepsy in children, with the consideration of both medical and surgical treatment options.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Pathogenic variants have additive effect on ALS survival
Genetic variants that modify survival in amyotrophic lateral sclerosis (ALS) can act on their own or in unison, having an additive effect and significantly worsening a patient’s outcome, researchers report in the journal Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Glucocorticoid withdrawal prevalent and persistent after hypercortisolism surgery
Myalgias and arthralgias are prominent symptoms associated with glucocorticoid withdrawal syndrome following surgical remission of endogenous hypercortisolism, report Irina Bancos, from the Mayo Clinic in Rochester, Minnesota, USA, and colleagues.
Urinary DKK3 signals declining kidney function and treatment response in children
Increased urinary Dickkopf-related protein 3 levels could indicate declining kidney function in children with chronic kidney disease and be a marker of treatment response, report researchers in The Lancet Child and Adolescent Health.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Autoantibodies may identify Sjögren’s syndrome in Ro-negative patients
The use of autoantibody biomarkers could be a feasible way of identifying Sjögren’s syndrome in patients lacking the anti-Ro antibody without the need for a salivary gland lip biopsy, suggests a proof-of-concept study.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Intracerebral polio–rhinovirus immunotherapy feasible for paediatric malignant glioma
Intracerebral recombinant polio–rhinovirus immunotherapy is feasible in children and young people with heavily pretreated, high-grade malignant glioma, suggest phase 1b trial findings published in The Lancet Child & Adolescent Health.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Serious infection risk not increased by rituximab and belimumab in SLE
Neither rituximab nor belimumab significantly increase the risk for serious infection in patients with systemic lupus erythematosus compared with the standard of care, researchers report.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
