VROOM trial: Pausing methotrexate doubles antibody response to COVID-19 booster vaccine
Holding methotrexate treatment for 2 weeks following administration of a booster dose of vaccines against SARS-CoV-2 significantly improves the humoral immune response to vaccination, suggest findings from a randomized controlled trial.
Maintenance therapy discontinuation may be risky in proliferative lupus nephritis
Individuals who discontinue maintenance immunosuppressive therapy for proliferative lupus nephritis after 2–3 years have a higher rate of relapse and severe flares than those who continue with treatment, suggest data from the WIN-Lupus trial.
TNF inhibitor tapered T2T strategy feasible in PsA and axSpA
A tapering treat-to-target strategy can lead to a large reduction in TNF inhibitor dose without impacting disease control in people with psoriatic arthritis or axial spondyloarthritis, study findings indicate.