Study identifies sex differences in RA remission rates
Men with rheumatoid arthritis initiating treatment with biologic or targeted synthetic DMARDs may be more likely to achieve remission than women, suggests research reported at The Lancet Summit: Sex and gender in rheumatology.
SEMAPHORE: Tocilizumab reduces disease activity in steroid-dependent polymyalgia rheumatica
The IL-6 receptor inhibitor tocilizumab may significantly reduce disease activity and the amount of prednisone needed in people with glucocorticoid-dependent active polymyalgia rheumatica, suggest results from a phase 3 trial published in JAMA.
Online yoga program shows limited benefits for knee osteoarthritis
People with knee osteoarthritis may experience modest improvements in physical function while following a 12-week self-guided online yoga program, but the benefits are not sustained when the exercise is stopped, researchers report.
Pregnancy outcome data ‘reassuring’ for women with axSpA
Women with axial spondyloarthritis have “very low” rates of adverse pregnancy outcomes, show observational data from European pregnancy registries.
CV risk reduction should be ‘an integral part’ of autoimmune disease management
A large study published in The Lancet has found that people with autoimmune diseases have an approximately 1.4–3.6-fold increased risk for developing cardiovascular disease relative to the general population.
‘Substantial improvement’ in COVID-19 outcomes over time for RMD patients
The proportion of people with rheumatic and musculoskeletal diseases experiencing severe COVID-19 has declined since the beginning of the pandemic, particularly during the recent Omicron wave, US researchers report.
Genetic study emphasizes ‘central role’ of complement pathway in SLE, pSS
A combination of partial deficiencies affecting the C2 and C4A classical complement pathway genes may represent a risk factor for the development of systemic lupus erythematosus or primary Sjögren’s syndrome, shows research from Lars Rönnblom and team.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
More efforts needed to improve gender equity in academic rheumatology
Findings from two studies highlight the need for interventions to improve gender equity in academic rheumatology career advancement and on journal editorial boards.
Pioglitazone may modulate CVD risk in patients with SLE
Pioglitazone, a peroxisome proliferator activated receptor-γ agonist, is associated with improvements in vascular stiffness and various cardiometabolic parameters in patients with systemic lupus erythematosus, show study findings.
Gout flares linked to temporary increase in cardiovascular risk
Gout flares are associated with an increased risk for cardiovascular events in the following 120 days, study findings suggest.
