Physical frailty identified as possible target in Parkinson’s disease prevention

Physical frailty may be a risk factor for Parkinson’s disease, particularly in people with a high genetic risk for the condition, suggest study findings published in JAMA Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Baricitinib disappoints in SLE-BRAVE trials

Baricitinib has achieved largely negative results in the SLE-BRAVE trials, published in The Lancet.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Promising results for focused ultrasound ablation in Parkinson’s disease

Focused ultrasound ablation of the globus pallidus internus improved symptoms in a substantial proportion of people with Parkinson’s disease in a randomised trial, but it comes with side effects.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Mild gestational glucose intolerance tied to future type 2 diabetes risk

Impaired glucose tolerance during pregnancy that does not meet the criteria for gestational diabetes nevertheless increases the likelihood that women will later develop type 2 diabetes, a study shows.
LAMP2: Atropine eyedrops may reduce myopia incidence in children

Children using nightly atropine eyedrops have a significantly lower incidence of myopia during 2 years of use than those using placebo, show the findings of the LAMP2 randomised trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Reflux symptoms predict interstitial lung disease progression in SSc

Post-hoc analysis of a randomised trial shows that the severity of reflux symptoms in patients with systemic sclerosis predicts radiographic progression of interstitial lung disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Anthracycline heart failure risk quantified for breast cancer, lymphoma patients

Patients who receive an anthracycline during treatment for breast cancer or lymphoma are more than three times as likely to develop congestive heart failure than healthy individuals, indicates a case–control study published in JAMA Network Open.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Health informatics system aids timely, equitable diabetes care

A health informatics system based on routine clinical data helps physicians to prioritize high-risk people with diabetes, deliver more equitable care, and manage healthcare capacity, report researchers.
Autoantibodies precede ulcerative colitis by up to a decade

The appearance of autoantibodies against integrin αvβ6 precedes the onset of ulcerative colitis by up to 10 years and is associated with disease severity, report researchers.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
PRIME II ‘extremely reassuring’ on radiotherapy omission in older women with early breast cancer

The 10-year data from the PRIME II trial suggest that radiotherapy after breast-conserving surgery can be omitted for women aged 65 years or older with low-risk, hormone receptor-positive early breast cancer.