AAV2 blamed for acute hepatitis outbreak in children
Three papers published in Nature have linked infection with adeno-associated virus 2 to the recent outbreak of acute severe hepatitis in children.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
‘Multihit’ gastric cancer risk from H. pylori plus cancer-predisposing variants
The presence of Helicobacter pylori alongside pathogenic variants in cancer-predisposing genes combine to increase the risk for gastric cancer, report researchers in The New England Journal of Medicine.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Neurodevelopment impairment common in FNAIT regardless of intracranial haemorrhage
Children with foetal neonatal alloimmune thrombocytopenia are at high risk of impaired neurodevelopment, especially if they have experienced intracranial haemorrhage, shows research in The Journal of Pediatrics.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Haplo-SCT plus dinutuximab beta ‘feasible’ for relapsed high-risk neuroblastoma
Children with relapsed, high-risk neuroblastoma may benefit from immunotherapy with dinutuximab beta after haploidentical stem-cell transplantation, investigators write in the Journal of Clinical Oncology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Physical frailty identified as possible target in Parkinson’s disease prevention
Physical frailty may be a risk factor for Parkinson’s disease, particularly in people with a high genetic risk for the condition, suggest study findings published in JAMA Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Baricitinib disappoints in SLE-BRAVE trials
Baricitinib has achieved largely negative results in the SLE-BRAVE trials, published in The Lancet.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Promising results for focused ultrasound ablation in Parkinson’s disease
Focused ultrasound ablation of the globus pallidus internus improved symptoms in a substantial proportion of people with Parkinson’s disease in a randomised trial, but it comes with side effects.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Mild gestational glucose intolerance tied to future type 2 diabetes risk
Impaired glucose tolerance during pregnancy that does not meet the criteria for gestational diabetes nevertheless increases the likelihood that women will later develop type 2 diabetes, a study shows.
Age-specific CS differences may complicate diagnosis in older patients
Older adults with Cushing’s syndrome are less likely than younger patients to present with typical symptoms of cortisol excess, report Elena Valass and co-researchers.
LAMP2: Atropine eyedrops may reduce myopia incidence in children
Children using nightly atropine eyedrops have a significantly lower incidence of myopia during 2 years of use than those using placebo, show the findings of the LAMP2 randomised trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
