LAMP2: Atropine eyedrops may reduce myopia incidence in children

Children using nightly atropine eyedrops have a significantly lower incidence of myopia during 2 years of use than those using placebo, show the findings of the LAMP2 randomised trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Reflux symptoms predict interstitial lung disease progression in SSc

Post-hoc analysis of a randomised trial shows that the severity of reflux symptoms in patients with systemic sclerosis predicts radiographic progression of interstitial lung disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Anthracycline heart failure risk quantified for breast cancer, lymphoma patients

Patients who receive an anthracycline during treatment for breast cancer or lymphoma are more than three times as likely to develop congestive heart failure than healthy individuals, indicates a case–control study published in JAMA Network Open.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Health informatics system aids timely, equitable diabetes care

A health informatics system based on routine clinical data helps physicians to prioritize high-risk people with diabetes, deliver more equitable care, and manage healthcare capacity, report researchers.
Autoantibodies precede ulcerative colitis by up to a decade

The appearance of autoantibodies against integrin αvβ6 precedes the onset of ulcerative colitis by up to 10 years and is associated with disease severity, report researchers.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
PRIME II ‘extremely reassuring’ on radiotherapy omission in older women with early breast cancer

The 10-year data from the PRIME II trial suggest that radiotherapy after breast-conserving surgery can be omitted for women aged 65 years or older with low-risk, hormone receptor-positive early breast cancer.
iNTEGRATE fails to demonstrate significant cGVHD benefit for ibrutinib–prednisone regimen

Combining ibrutinib and prednisone for the treatment of new-onset chronic graft-versus-host disease after allogeneic haematopoietic cell transplantation does not improve patient response compared with prednisone alone, show phase 3 trial findings published in the Journal of Clinical Oncology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Study sheds light on genetic cause of late-onset cerebellar ataxia

A dominantly inherited, intronic repeat expansion in the fibroblast growth factor 14 gene is associated with late-onset cerebellar ataxia, shows research published in The New England Journal of Medicine.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Impaired motor development flags psychosis risk in susceptible children

Children with a high familial risk of psychosis have an increased risk of motor impairments, which are stable over time and linked to the likelihood of having psychotic experiences, research shows.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Maintenance darolutamide shows promise in metastatic CRPC

Phase 2 data point to the potential of switch maintenance with darolutamide in men with metastatic castration-resistant prostate cancer that has not progressed after taxane therapy.