Share

|

|

|

Blood immunoassay shows high diagnostic accuracy for Alzheimer’s disease pathology

Elderly woman in hospital room with doctor and nurse. Neurologist holding anatomical model of human brain, conceptual image

A commercially available plasma phosphorylated (p)-tau217 immunoassay outperforms other biomarkers in accurately identifying biological Alzheimer’s disease, suggest findings from a study across three observational cohorts.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Add-on telitacicept improves clinical response in patients with active SLE

Telitacicept used in addition to standard therapy shows promising efficacy in Chinese patients with active systemic lupus erythematosus, suggests a phase 2b trial published in the Annals of the Rheumatic Diseases.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Cerliponase alfa treatment shows extended efficacy for CLN2 disease

Cerliponase alfa treatment slows the progression of neuronal ceroid lipofuscinosis type 2 disease for at least 5 years, shows an open-label extension study in The Lancet Neurology.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

VTE rates not significantly reduced by apixaban in paediatric ALL or lymphoma

Apixaban does not significantly reduce the rate of venous thromboembolism relative to standard care in paediatric patients with acute lymphoblastic leukaemia or lymphoma, show data from the phase 3 PREVAPIX-ALL trial.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Respiratory infection risk heightened in primary Sjögren’s syndrome and ILD

Patients with primary Sjögren’s syndrome and interstitial lung disease are at increased risk of respiratory infections, particularly bacterial infections, suggests a study published in Clinical Rheumatology.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Zonulin shows biomarker potential for celiac disease in at-risk children

Serum levels of the protein zonulin, high levels of which are associated with increased intestinal permeability, may be a useful biomarker for the development of celiac disease autoimmunity in children at genetic risk of the condition, suggest findings from the CD-GEMMA study.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Remibrutinib shows promise for Sjögren’s syndrome treatment

The Bruton’s tyrosine kinase inhibitor remibrutinib reduces disease activity in patients with Sjögren’s syndrome, show results from the phase 2 LOUiSSE trial.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Young age reduces MS disability but does not fully protect against it

Progression of multiple sclerosis in the absence of relapses can occur at any age, although it is less common in children than adults with the condition, suggests research.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.