Reflux symptoms predict interstitial lung disease progression in SSc
Post-hoc analysis of a randomised trial shows that the severity of reflux symptoms in patients with systemic sclerosis predicts radiographic progression of interstitial lung disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Anti-dsDNA antibodies could predict response to B cell-targeted therapies in SLE
IgA2 anti-dsDNA antibodies may represent a biomarker of response to B cell-targeted therapies in patients with systemic lupus erythematosus, suggest study findings from Michael Ehrenstein and colleagues.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Research identifies sex differences in SSc-ILD outcomes
Men with systemic sclerosis-associated interstitial lung disease may have a more severe disease course than women, whereas women with the condition could be more likely to experience certain adverse events when treated with immunosuppressive therapy, suggest findings from two studies.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Prophylactic antivirals may help prevent symptomatic COVID-19 in rituximab-treated patients
Pre-exposure prophylaxis with tixagevimab and cilgavimab may be an effective strategy to prevent symptomatic SARS-CoV-2 infection among people with rheumatic diseases treated with rituximab, suggest findings from a real-world study.
Support for JAK inhibitors as ‘drug of choice’ for patients with PsA and significant joint disease
JAK inhibitors show promise for the treatment of moderate-to-severe psoriasis and psoriatic arthritis, finds a systematic review and meta-analysis of more than 6000 patients.
Study identifies sex differences in RA remission rates
Men with rheumatoid arthritis initiating treatment with biologic or targeted synthetic DMARDs may be more likely to achieve remission than women, suggests research reported at The Lancet Summit: Sex and gender in rheumatology.
SEMAPHORE: Tocilizumab reduces disease activity in steroid-dependent polymyalgia rheumatica
The IL-6 receptor inhibitor tocilizumab may significantly reduce disease activity and the amount of prednisone needed in people with glucocorticoid-dependent active polymyalgia rheumatica, suggest results from a phase 3 trial published in JAMA.
Online yoga program shows limited benefits for knee osteoarthritis
People with knee osteoarthritis may experience modest improvements in physical function while following a 12-week self-guided online yoga program, but the benefits are not sustained when the exercise is stopped, researchers report.
Pregnancy outcome data ‘reassuring’ for women with axSpA
Women with axial spondyloarthritis have “very low” rates of adverse pregnancy outcomes, show observational data from European pregnancy registries.
CV risk reduction should be ‘an integral part’ of autoimmune disease management
A large study published in The Lancet has found that people with autoimmune diseases have an approximately 1.4–3.6-fold increased risk for developing cardiovascular disease relative to the general population.
