Caffeine promotes endothelial progenitor cell survival in SLE
Caffeine may protect against endothelial dysfunction in patients with systemic lupus erythematosus, suggest Italian researchers.
Predictors of MALT lymphoma in Sjögren’s disease characterised
Researchers have identified rheumatoid factor as an early and persistent independent predictor of mucosa-associated lymphoid tissue lymphoma in patients with Sjögren’s disease.
Adjuvanted herpes zoster subunit vaccine induces immunity in patients with SLE
The adjuvanted herpes zoster subunit vaccine induces both humoral and cellular immunity in patients with systemic lupus erythematosus, without increasing the risk of disease flare, suggests research from South Korea.
Scoring system devised for stratifying children with suspected Sjögren’s syndrome
Researchers have devised the Florida Scoring System to help clinicians stratify children with suspected Sjögren’s syndrome into three distinct classes, thereby improving diagnosis and disease monitoring.
CAR T cells show promise for treatment of autoimmune diseases
CD19 chimeric antigen receptor T-cell therapy appears to be “feasible, safe, and efficacious” for the treatment of three autoimmune diseases, researchers report.
Mycophenolate mofetil withdrawal feasible in SLE patients with stable disease
Patients with systemic lupus erythematosus may be able to stop taking mycophenolate mofetil once their condition becomes stable without significantly increasing their risk for flare compared with continuing treatment, suggests an open-label, randomized controlled trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Add-on telitacicept improves clinical response in patients with active SLE
Telitacicept used in addition to standard therapy shows promising efficacy in Chinese patients with active systemic lupus erythematosus, suggests a phase 2b trial published in the Annals of the Rheumatic Diseases.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Respiratory infection risk heightened in primary Sjögren’s syndrome and ILD
Patients with primary Sjögren’s syndrome and interstitial lung disease are at increased risk of respiratory infections, particularly bacterial infections, suggests a study published in Clinical Rheumatology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Remibrutinib shows promise for Sjögren’s syndrome treatment
The Bruton’s tyrosine kinase inhibitor remibrutinib reduces disease activity in patients with Sjögren’s syndrome, show results from the phase 2 LOUiSSE trial.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Diffusing capacity of lung for carbon monoxide predicts SLE disease severity
The diffusing capacity of the lungs for carbon monoxide could be a surrogate marker for overall disease severity in patients with systemic lupus erythematosus, suggest researchers in Rheumatology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
