Bevacizumab addition to temozolomide chemotherapy may improve neuroblastoma response
Findings from the BEACON-Neuroblastoma trial suggest that adding bevacizumab to temozolomide-based chemotherapy may improve the objective response rate for children with high-risk, relapsed or refractory disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Cerliponase alfa treatment shows extended efficacy for CLN2 disease
Cerliponase alfa treatment slows the progression of neuronal ceroid lipofuscinosis type 2 disease for at least 5 years, shows an open-label extension study in The Lancet Neurology.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Zonulin shows biomarker potential for celiac disease in at-risk children
Serum levels of the protein zonulin, high levels of which are associated with increased intestinal permeability, may be a useful biomarker for the development of celiac disease autoimmunity in children at genetic risk of the condition, suggest findings from the CD-GEMMA study.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Young age reduces MS disability but does not fully protect against it
Progression of multiple sclerosis in the absence of relapses can occur at any age, although it is less common in children than adults with the condition, suggests research.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Fingerstick blood test cartridge may improve childhood TB diagnosis
A three-gene Mycobacterium tuberculosis host response cartridge using a fingerstick blood sample has shown promising diagnostic accuracy for childhood tuberculosis, researchers report in The Lancet Infectious Diseases.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Rationale for antiviral therapy in new-onset type 1 diabetes
Antiviral therapy may preserve residual insulin production in children and adolescents newly diagnosed with type 1 diabetes, suggest findings from the DiViD intervention study.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Four distinct Kawasaki disease subgroups identified
Distinct subgroups exist among children with Kawasaki disease, say researchers in findings that provide some clues to the clinical variability of the disease.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Brain imaging aids long-term outcome prediction in paediatric cardiac arrest
Research suggests that magnetic resonance imaging and magnetic resonance spectroscopy conducted within 2 weeks of a cardiac arrest may help determine longer-term outcomes in children.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Early surgery improves survival for children with drug-resistant epilepsy
Study findings highlight the importance of a multidisciplinary comprehensive approach to drug-resistant epilepsy in children, with the consideration of both medical and surgical treatment options.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
Urinary DKK3 signals declining kidney function and treatment response in children
Increased urinary Dickkopf-related protein 3 levels could indicate declining kidney function in children with chronic kidney disease and be a marker of treatment response, report researchers in The Lancet Child and Adolescent Health.
This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.
