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Cerliponase alfa treatment shows extended efficacy for CLN2 disease

Cerliponase alfa treatment slows the progression of neuronal ceroid lipofuscinosis type 2 disease for at least 5 years, shows an open-label extension study in The Lancet Neurology.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Zonulin shows biomarker potential for celiac disease in at-risk children

Serum levels of the protein zonulin, high levels of which are associated with increased intestinal permeability, may be a useful biomarker for the development of celiac disease autoimmunity in children at genetic risk of the condition, suggest findings from the CD-GEMMA study.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Young age reduces MS disability but does not fully protect against it

Progression of multiple sclerosis in the absence of relapses can occur at any age, although it is less common in children than adults with the condition, suggests research.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Fingerstick blood test cartridge may improve childhood TB diagnosis

A three-gene Mycobacterium tuberculosis host response cartridge using a fingerstick blood sample has shown promising diagnostic accuracy for childhood tuberculosis, researchers report in The Lancet Infectious Diseases.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Rationale for antiviral therapy in new-onset type 1 diabetes

Antiviral therapy may preserve residual insulin production in children and adolescents newly diagnosed with type 1 diabetes, suggest findings from the DiViD intervention study.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Four distinct Kawasaki disease subgroups identified

Distinct subgroups exist among children with Kawasaki disease, say researchers in findings that provide some clues to the clinical variability of the disease.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Early surgery improves survival for children with drug-resistant epilepsy

Study findings highlight the importance of a multidisciplinary comprehensive approach to drug-resistant epilepsy in children, with the consideration of both medical and surgical treatment options.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Urinary DKK3 signals declining kidney function and treatment response in children

Increased urinary Dickkopf-related protein 3 levels could indicate declining kidney function in children with chronic kidney disease and be a marker of treatment response, report researchers in The Lancet Child and Adolescent Health.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.