Childhood hypertension linked to threefold increased risk of kidney disease
Paediatric hypertension is associated with a significantly increased long-term risk of major adverse kidney events, suggests research published in The Lancet Child & Adolescent Health.
Childhood cancer survivors might benefit from cochlear implants
Childhood cancer survivors with severe to profound sensorineural hearing loss following chemotherapy or radiotherapy may be candidates for cochlear implants, US researchers believe.
‘Accelerated’ onset of aging-related disease highlighted for childhood cancer survivors
Children who survive for at least 5 years after treatment for cancer are 2.7 times more likely to develop one of eight aging-related chronic health conditions before the age of 65 years than members of the general population, US researchers suggest.
Larotrectinib discontinuation possible for some paediatric NTRK fusion-positive tumours
Children who respond to larotrectinib therapy for sarcoma with a neurotrophic tyrosine receptor kinase gene fusion may be able to discontinue treatment, indicates research published in the Journal of Clinical Oncology.
Primary MMR deficiency ‘underdiagnosed’ among young people with glioma
Primary mismatch repair deficiency in gliomas is underdiagnosed among people younger than 40 years old, say investigators who recommend assessment of the biomarker to help facilitate checkpoint inhibitor therapy.
Hypertension perseveres from childhood and adolescence to adulthood
High blood pressure or hypertension in childhood or adolescence appears to endure into adulthood, report researchers in findings that support early prevention.
European retinoblastoma report shows stabilised incidence, high 5-year survival
The incidence of retinoblastoma in children in Europe stabilised between 2000 and 2013, say EUROCARE-6 Working Group investigators who report high 5-year survival rates in this population.
Fear of recurrence persists for decades among paediatric cancer survivors
A third of adults who survive childhood cancer continue to have a fear of cancer recurrence for decades after their diagnosis, highlights research published in JAMA Network Open.
Paediatric HCT for nonmalignant illness requires lifelong follow-up
Children and adolescents who undergo allogeneic haematopoietic stem cell transplantation for nonmalignant disease require “multidisciplinary and lifelong follow-up”, researchers recommend in The Lancet Child & Adolescent Health.
Perioperative opioid use in US youths often not in line with guidelines
Many children and adolescents are receiving opioid prescriptions for prolonged periods after inpatient or outpatient surgical procedures, which is outside the guidelines for their use, suggests research published in JAMA Network Open.
