Stroke

People with osteoarthritis are significantly more likely than those without to have multiple comorbidities, particularly stroke, peptic ulcers, and the metabolic syndrome, show results of a systematic review and meta-analysis of observational data.

Survivors of ischemic stroke are more likely to be diagnosed with cancer than the general population, a chart review suggests.

IPSYS investigators have found a significant association between migraine and cervical artery dissection, identifying it as a potential biomarker.

Research published in JAMA suggests that suboptimal intake of specific dietary factors is associated with almost half of deaths from heart disease, stroke, or type 2 diabetes in the USA.

Patients with ischemic stroke or transient ischemic attack of atherosclerotic origin may gain more benefit from taking ticagrelor than aspirin, study findings in The Lancet Neurology indicate.

A Danish nationwide cohort study published in The BMJ examines the effectiveness and safety profiles of novel oral anticoagulants among patients with atrial fibrillation.

 Collateral blood vessels detected on arterial spin labeling magnetic resonance imaging are significantly associated with good neurologic outcomes in patients after acute ischemic stroke.

Research suggests that all patients aged 60 years or older who have had a stroke, irrespective of the suspected cause, could benefit from enhanced and prolonged monitoring for atrial fibrillation.

Surgical patients with a history of migraine are at increased risk for perioperative ischemic stroke and hospital readmission within 30 days, study findings indicate.

Irrigation with alteplase to remove intraventricular hemorrhage in patients with intracerebral hemorrhage and a routine extraventricular drain does not substantially improve functional outcome, indicate findings from the CLEAR III trial.

Results of a study conducted in primates suggest that a novel protease-activated receptor-4 antagonist could reduce thrombus formation with a lower bleeding risk than other antiplatelet agents.

Ischemic conditioning has no effect on the risk of all-cause mortality in patients undergoing invasive procedures, results of a meta-analysis suggest.

Irreversibly damaged tissue should not rule out endovascular treatment for acute ischemic stroke for all patients, case–control study findings in JAMA Neurology suggest.

Researchers are calling for a broader role for acute-phase magnetic resonance imaging in patients with intracerebral haemorrhage after finding it identifies features of small vessel disease that are independently associated with haematoma expansion.

Early initiation of endovascular stroke treatment is critical to give patients the best chance of achieving functional independence, say the HERMES collaborators.

An analysis of the US Get With The Guidelines–Stroke registry has revealed multiple patient and hospital characteristics associated with failure to provide intravenous tissue plasminogen activator therapy in eligible patients with acute ischaemic stroke.

Edoxaban appears to be an effective alternative to warfarin and enoxaparin bridging for cardioversion of patients with non-valvular atrial fibrillation, findings from a phase IIIb trial show.

A US research team reports mixed results for a placebo-controlled phase II trial of intravenous glyburide in patients presenting with a large hemispheric infarction and at risk for cerebral oedema.

THRACE study findings confirm the benefits of rapid mechanical thrombectomy after intravenous alteplase in a broad range of patients with acute ischaemic stroke.

Researchers call for trials of blood transfusion in stroke patients who have anaemia.