NICE recommends upadacitinib for some PsA patients
medwireNews: The National Institute for Health and Care Excellence has recommended upadacitinib as a treatment option for certain patients with active psoriatic arthritis (PsA) in England and Wales.
The selective Janus kinase 1 inhibitor may now be used for adult patients with peripheral PsA and at least three tender and three swollen joints despite prior treatment. To be eligible for upadacitinib patients must either:
have an inadequate response to at least two conventional DMARDs and one biologic DMARD; orhave a contraindication to tumor necrosis factor inhibitors when they would otherwise be considered.
The benefits of upadacitinib for people with PsA were demonstrated in the SELECT-PsA-1 and SELECT-PsA-2 trials.
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