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11-04-2010 | Respiratory | Article

Sweat response increased in asthmatic children


Free abstract

MedWire News: Boys, but not girls, with asthma sweat more in response to physical exercise than those without the respiratory condition, results from a Turkish study show.

Writing in the journal Allergy, O Kalayci (Hacettepe University School of Medicine, Ankara) and team explain: “Even though there is a general conviction among parents of asthmatic children and pediatricians that asthmatic children sweat more than healthy ones, this has not been formally tested.”

To investigate, the researchers studied 82 children with asthma and 51 non-asthmatic healthy children without any other significant chronic diseases who were aged 6–18 years.

The researchers measured transepidermal water loss (TEWL) on palm, volar, mid-forehead, and back skin before and after the children had exercised on a treadmill for 6 minutes or until heart rate had reached 80% of the age-predicted maximum.

They found that TEWL on palm skin was higher in asthmatic than non-asthmatic children after exercise, at 22.8 g/m2 h versus 15.2 g/m2h. Similar differences between the groups were observed for TEWL on volar, mid-forehead, and back skin.

Further analysis showed that these differences in TEWL measurements occurred in boys, but not girls.

The researchers also found that, in asthmatic children, those taking anti-inflammatory medications had lower TEWL measurements than those who were not taking such medications.

Kalayci and team conclude: “Our results show that asthma is associated with a higher rate of sweating response to exercise in boys, and anti-inflammatory treatment decreases the amount of sweating.”

They add: “The relationship of eccrine sweating with muscarinic receptor response and methacholine hyper-responsiveness remains to be determined.”

MedWire ( is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Mark Cowen

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