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Obstetrics and gynaecology

Obstetrics and gynaecology


21-07-2016 | Breast cancer | News | Article

Breast cancer risk reassurance for IVF-treated women

Women who receive in vitro fertilisation treatment do not have a higher risk of developing breast cancer in the long term versus those who receive non-IVF therapy and the general population, say Dutch researchers.

13-06-2016 | HBV | News | Article

Maternal HBsAg can serve as HBV vertical transmission marker

Two studies have independently identified quantitative hepatitis B surface antigen as a marker to identify pregnant women with chronic hepatitis B virus infection whose infants are at high-risk of infection despite immunoprophylaxis.

24-05-2016 | Neurology | News | Article

Low-dose rhEPO may reap neuroprotective benefits for preterm infants

Clarification of the dose and duration at which to give recombinant human erythropoietin to preterm infants may be key to realising its neuroprotective properties.

19-05-2016 | Neurology | News | Article

Maternal pregabalin exposure linked to major birth defect risk

First trimester exposure to pregabalin may be associated with an increased risk of major birth defects, an observational study suggests.

18-05-2016 | Neurology | News | Article

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants

Very preterm infants do not gain protection against neurodevelopmental delay with early prophylactic high-dose recombinant human erythropoietin, researchers report.

13-05-2016 | Diabetes | News | Article

Pre-existing maternal diabetes still major risk factor for congenital heart defects

The strong influence of pre-pregnancy diabetes on the likelihood of women giving birth to babies with congenital heart defects has not lessened over recent decades, say researchers.

Newborn screening

05-05-2016 | Neurology | Highlight | Article

Newborn screen for Niemann–Pick disease type C ready for piloting

Researchers have developed a bile acid-based test that they believe could help screen for Niemann–Pick disease type C in newborns.

07-04-2016 | Epilepsy | News | Article

Epilepsy drug exposure does not increase newborn orofacial cleft risk

Pregnant women with epilepsy should not rule out continuing lamotrigine therapy due to concerns that exposure could increase the risk of orofacial clefts in their babies, say investigators.

07-04-2016 | Oncology | News | Article

Ovarian cancer HRQoL ‘not compromised’ with trebananib

Treatment with the antiangiogenesis inhibitor trebananib does not adversely affect health-related quality of life in patients with recurrent ovarian cancer, suggests the placebo-controlled TRINOVA-1 trial.


30-03-2016 | Oncology | News | Article

Fertility ‘reassurance’ for most chemotherapy-treated female childhood cancer survivors

Both female and male chemotherapy-treated survivors of childhood cancer have an increased risk of impaired fertility, but results suggest that the risk in women is limited to those given specific chemotherapy drugs.

04-02-2016 | Oncology | News | Article

Oncofertility complications reviewed for US patients

Three articles published in JAMA Oncology highlight the legal and clinical care issues surrounding fertility preservation in US patients with cancer.


10-08-2015 | Oncology | News | Article

Meta-analysis confirms oral contraceptives reduce endometrial cancer risk

Oral contraceptive use protects against endometrial cancer, with effects persisting for decades after cessation of use, shows a meta-analysis of individual patient data published in The Lancet Oncology.

04-08-2015 | Epilepsy | News | Article

Antiepileptic monotherapy does not increase intrauterine death risk

Neither type nor dosage of antiepileptic drug affects the risk of intrauterine death among pregnant women with epilepsy when given as monotherapy, suggests research.

Pregnant woman_blood test

16-07-2015 | Oncology | Article

Noninvasive prenatal testing clue to maternal malignancy

A preliminary study lends support to the hypothesis that a false-positive noninvasive prenatal test finding could be due to the presence of an occult maternal cancer.


26-06-2015 | Oncology | News | Article

No overall survival benefit for bevacizumab in ovarian cancer

Addition of bevacizumab to first-line platinum-based chemotherapy does not improve overall survival in women with ovarian cancer, according to the mature data of the ICON7 trial.


17-06-2015 | Oncology | News | Article

Bivalent HPV vaccine efficacy may be independent of dose

Fewer than three doses of the bivalent human papillomavirus vaccine may be sufficient to offer adequate protection against cervical HPV-16 and -18 infection, research published in The Lancet Oncology indicates.

21-09-2014 | Gynaecology | Article

OABSS reveals impact of symptoms on women’s quality of life

The Overactive Bladder Symptom Score questionnaire is valuable for assessing the impact of OAB symptoms on women’s health-related quality of life, shows a large survey of Japanese women.

31-08-2014 | Gynaecology | Article

Transobturator tape improves OAB symptoms including nocturia

The use of transobturator tape offers significant relief from symptoms of overactive bladder in patients with mixed urinary incontinence, study findings indicate.

31-08-2014 | Gynaecology | Article

Drugs plus biofeedback show promise for dysfunctional voiding

Research shows that the use of α1-blockers in combination with uroflowmetry biofeedback is more effective than either treatment alone for improving urinary symptoms and quality of life in women with dysfunctional voiding and recurrent urinary tract infection.

24-08-2014 | Gynaecology | Article

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.