Obstetrics and gynaecology

The EMPOWER-Cervical 1 trial findings demonstrate a significant survival advantage with cemiplimab versus investigator’s choice of chemotherapy for women with recurrent or metastatic cervical cancer that has progressed after treatment with platinum-containing chemotherapy.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

The significantly increased risk for type 2 diabetes after a diagnosis of gestational diabetes mellitus persists for over 35 years, suggests a study published in Diabetes Care.

A nationwide study of Swedish breast cancer patients has demonstrated that receipt of fertility preservation significantly improves reproductive outcomes compared with the absence of such care.

The ACR has released guidelines for reproductive healthcare among people with rheumatic and musculoskeletal diseases.

Women with rheumatoid arthritis should avoid medium to high levels of oral corticosteroids during early or late pregnancy, say researchers who found an association with increased risk for preterm birth.

A Scottish study has identified glycated hemoglobin levels and BMI as modifiable risk factors for stillbirth among pregnant women with diabetes.

Evidence-based recommendations for the management of antiphospholipid syndrome in adult patients have been issued by EULAR.

Women with infertility have a significantly higher risk than those without for both hormonal and nonhormonal cancers, but the absolute risk in both groups is low, shows an analysis of US insurance claims data.

Using continuous glucose monitoring for all women with type 1 diabetes during pregnancy could save the UK National Health Service over 9 million pounds per year, report the CONCEPTT investigators.

Children conceived using assisted reproductive technology do not have an increased cancer risk relative to either the general population or naturally conceived children of women with impaired fertility, shows a Dutch study with a long follow-up.

Women with rheumatoid arthritis have a significantly lower chance of having a live birth following assisted reproductive technology treatment than women without RA, researchers report in the Annals of the Rheumatic Diseases.

Women with polycystic ovary syndrome may have an increased likelihood for developing cancer, although the excess risk appears to be primarily restricted to those who are premenopausal, indicates a population-based study.

Progression-free survival is significantly improved with the use of maintenance olaparib in women with newly diagnosed FIGO stage III or IV ovarian cancer and a BRCA1/2 mutation, shows the placebo-controlled SOLO1 trial.

The use of hormonal contraceptives just before and during pregnancy may significantly increase the risk for childhood non-lymphoid leukemia, Danish researchers report.

Women with rheumatoid arthritis and those with juvenile idiopathic arthritis have a significantly elevated risk for preterm delivery, according to a prospective cohort study published in Arthritis Care & Research.

US researchers have found evidence to support catch-up vaccination against the human papillomavirus in women given their first dose in older adolescence.

Oral etoposide plus apatinib is associated with a good objective response rate and manageable toxicity in heavily pretreated Chinese women with platinum-resistant or refractory ovarian cancer, according to results of the phase II AEROC study.

The birth rate for women who are relapse-free after treatment for Hodgkin lymphoma has risen in recent years, becoming comparable with that of the general population regardless of disease stage or treatment.

Women who undergo assisted reproduction may be at increased risk for in situ breast cancer, and invasive and borderline ovarian tumors, show results of a large, population-based study.

Women with inflammatory arthritis who discontinue tumor necrosis factor inhibitor therapy during pregnancy may be at increased risk for flare, researchers report.