FINDRISC questionnaire not suitable for detection of IGT
MedWire News: Study findings suggest that the Finnish Diabetes Risk Score (FINDRISC) questionnaire is a useful instrument for identifying individuals with impaired glucose metabolism, but is less effective for detection of impaired glucose tolerance (IGT).
"For ordinary primary healthcare units intending to identify individuals with impaired glucose tolerance for introduction of lifestyle changes, screening instruments need to be improved," say Margareta Hellgren (Sahlgrenska Academy at the University of Gothenburg, Sweden) and colleagues.
For the study, the researchers analyzed responses to the FINDRISC questionnaire completed by 5452 individuals aged 35-75 years living in Sweden. Individuals with a risk score of 15 or more were asked to undergo an oral glucose tolerance test (OGTT), while those with diabetes were excluded from the study.
The average risk score of the patients included in the study was 8.5, with 525 individuals scoring 15 or more. Administration of the OGTT among the 302 of these individuals revealed that 11% had previously undiagnosed Type 2 diabetes, 16% had IGT, and 29% had impaired fasting glucose (IFG).
Further analysis showed that the positive predictive value (PPV) of a FINDRISC score of 15 or more was 55% for impaired glucose metabolism, 11% for Type 2 diabetes, 16% for IGT, and 28% for IFG.
Raising the cutoff value to 17 did not significantly alter the PPV for IGT (17%), but increased it to 70% for impaired glucose metabolism. Increasing the cutoff point further did not significantly improve the PPV.
The study also showed that among individuals who scored 15 or more, the FINDRSIC questionnaire showed no significant differences in patient characteristics compared with patients scoring below 15, except that significantly more reported daily fruit and vegetable consumption (77.6 vs 66.4%).
"The characteristics and risks of patients with impaired fasting glucose should be further explored, and programs for screening and prevention developed for this condition," conclude the researchers in Diabetic Medicine.
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By Ingrid Grasmo