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26-04-2011 | Diabetes | Article

Diabetes may worsen post-PCI quality of life


Free abstract

MedWire News: Patients with diabetes have poorer health-related quality of life (HRQOL) at the time of percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and at 6 months after the procedure compared with those without diabetes, researchers report.

Being male and having an ST-elevation myocardial infarction (STEMI) also increase the likelihood of poor HRQOL after PCI, say Izabella Uchmanowicz, from Wroclaw Medical University in Poland, and team.

Reporting in the journal Acta Diabetologica, the researchers evaluated the baseline and 6-month post-PCI HRQOL of 120 ACS patients with a mean age of 62.5 years, using a self-administered questionnaire.

All patients underwent PCI following a non-ST-elevation myocardial infarction (NSTEMI; n=60) or STEMI (n=60).

When Uchmanowicz and colleagues analyzed the questionnaire results, they found that the group's physical and mental HRQOL scores significantly improved over the 6-month period, from 54.7 and 55.9, respectively, at baseline, to 55.5 and 56.5, respectively, at 6 months post-PCI.

The researchers note that diabetic patients (n=60) had worse baseline and 6-month HRQOL scores than nondiabetics, at 52.8 versus 56.6 and 53.4 versus 57.5, respectively, for physical HRQOL, and 53.8 versus 58.0 and 54.3 versus 58.7, respectively, for mental HRQOL.

Multivessel disease, high triglyceride levels, and arterial hypertension were also predictors of poor physical HRQOL, while high triglyceride levels and a history of myocardial infarction were associated with worse/poor mental HRQOL scores.

Uchmanowicz et al highlight that they observed a trend for women and NSTEMI patients to have worse baseline and 6-month HRQOL scores than all other patients, but that the reason for this is unclear.

The team therefore concludes that further study into HRQOL after cardiovascular events is required.

MedWire ( is an independent clinical news service provided by Springer Healthcare Limited. © Springer Healthcare Ltd; 2011

By Lauretta Ihonor

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