Regular screening helps reduce symptom burden in paediatric cancer patients

Research shows that young people with a recent diagnosis of cancer benefit from completing an online symptom screening survey three times a week to help direct care.
Caffeine promotes endothelial progenitor cell survival in SLE

Caffeine may protect against endothelial dysfunction in patients with systemic lupus erythematosus, suggest Italian researchers.
First-line trabectedin use boosts OS for advanced leiomyosarcoma

LMS-04 trial findings show a significant overall survival benefit with the use of induction and maintenance trabectedin alongside first-line doxorubicin for patients with inoperable, advanced leiomyosarcoma.
Annual screening supported for people at high-risk of pancreatic ductal adenocarcinoma

Findings from the Cancer of the Pancreas Screening program in the USA support the use of annual endoscopic ultrasound or magnetic resonance imaging for patients with a familial or genetic predisposition for pancreatic ductal adenocarcinoma.
Adjuvanted herpes zoster subunit vaccine induces immunity in patients with SLE

The adjuvanted herpes zoster subunit vaccine induces both humoral and cellular immunity in patients with systemic lupus erythematosus, without increasing the risk of disease flare, suggests research from South Korea.
Maralixibat improves itch, bile acid concentrations in paediatric PFIC

Treatment with the ileal bile acid transporter inhibitor maralixibat relieves morning itch for children with different types of progressive familial intrahepatic cholestasis, show phase 3 study findings published in The Lancet Gastroenterology and Hepatology.
FOXO1 fusion status aids paediatric local rhabdomyosarcoma risk assessment

Considering FOXO1 fusion status improves the risk assessment of children with localised rhabdomyosarcoma, suggest study findings published in Cancer.
Apitegromab shows motor function benefits in patients with SMA

Apitegromab improves motor function in patients with later-onset spinal muscular atrophy, show the results of the phase 2 TOPAZ study.
Home insulin pump use feasible for hospitalised children with type 1 diabetes

For children with type 1 diabetes who are admitted to hospital, continuing with a home insulin pump is feasible for the prevention of hyperglycemia and hypoglycemia, suggests research published in JAMA Network Open.
Autoimmune disease risk increased after surgical remission of Cushing’s disease

Patients with Cushing’s disease who achieve remission following surgery have an increased incidence of autoimmune disease, suggest findings published in the Annals of Internal Medicine in February 2024.