Predictors of MALT lymphoma in Sjögren’s disease characterised
Researchers have identified rheumatoid factor as an early and persistent independent predictor of mucosa-associated lymphoid tissue lymphoma in patients with Sjögren’s disease.
Salivary cortisol shows ‘excellent diagnostic performance’ for adrenal insufficiency
Salivary cortisol may be a suitable alternative to serum cortisol when testing for adrenal insufficiency, suggests research showing high diagnostic accuracy on the cosyntropin test.
Paediatric HCT for nonmalignant illness requires lifelong follow-up
Children and adolescents who undergo allogeneic haematopoietic stem cell transplantation for nonmalignant disease require “multidisciplinary and lifelong follow-up”, researchers recommend in The Lancet Child & Adolescent Health.
First-line trabectedin use boosts OS for advanced leiomyosarcoma
LMS-04 trial findings show a significant overall survival benefit with the use of induction and maintenance trabectedin alongside first-line doxorubicin for patients with inoperable, advanced leiomyosarcoma.
Circulating endocannabinoids potential biomarkers for ALS
Circulating endocannabinoids are associated with amyotrophic lateral sclerosis disease activity and progression, demonstrating potential prognostic value, report researchers in the European Journal of Neurology.
Annual screening supported for people at high-risk of pancreatic ductal adenocarcinoma
Findings from the Cancer of the Pancreas Screening program in the USA support the use of annual endoscopic ultrasound or magnetic resonance imaging for patients with a familial or genetic predisposition for pancreatic ductal adenocarcinoma.
Perioperative opioid use in US youths often not in line with guidelines
Many children and adolescents are receiving opioid prescriptions for prolonged periods after inpatient or outpatient surgical procedures, which is outside the guidelines for their use, suggests research published in JAMA Network Open.
Surveillance effective for childhood cancer predisposition syndrome management
Early detection of tumours in children with a cancer predisposition syndrome can be achieved with standardised surveillance protocols, US cohort study findings demonstrate.
Blood test predicts Parkinson’s disease up to 7 years before symptom onset
Researchers have used a machine learning approach to create a panel of eight blood biomarkers that can identify people at risk for developing Parkinson’s disease up to 7 years before the first signs or symptoms.
Phoenix Sepsis Score ‘accurate’ for children undergoing cancer treatment
The Phoenix Sepsis Score “accurately” characterises the risk of definitely attributable mortality from sepsis and the duration of intensive care unit stay in children undergoing cancer treatment who have a suspected infection, US researchers report.
