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Alzheimer's disease

Alzheimer's disease

11-10-2016 | Alzheimer's disease | News | Article

Verbal memory advantage in women may delay aMCI diagnosis

Women have a verbal memory advantage over men in the preclinical stages of Alzheimer’s disease that should be adjusted for in tests for the condition, researchers report.

06-09-2016 | Alzheimer's disease | News | Article

Antibody attacks beta-amyloid build up in early Alzheimer’s patients

Researchers have developed a human monoclonal antibody that selectively targets aggregated beta-amyloid and reduces its build up in the brains of patients with early-stage Alzheimer’s disease.

26-07-2016 | Alzheimer's disease | News | Article

Neurodegeneration does not necessarily signal cognitive decline

Neurodegeneration on its own does not significantly increase an individual’s risk of developing Alzheimer’s disease, indicate findings from a two-marker imaging study.

14-07-2016 | Alzheimer's disease | News | Article

Genetic risk factors signal AD susceptibility in the very young

Genetic risk factors for Alzheimer’s disease appear to have an early effect on the brain and may allow the detection of susceptible young individuals before symptoms are present, findings from two studies in Neurology suggest.

12-07-2016 | Parkinson's disease | News | Article

TBI linked to Parkinson’s disease in later life, but not dementia

Traumatic brain injury with loss of consciousness is associated with an increased risk for neurodegenerative conditions, but Alzheimer’s disease is not one of them, suggests research.

15-06-2016 | Alzheimer's disease | News | Article

Cerebral vessel disease increases Alzheimer’s dementia risk

Cerebral vessel disease may be an under-recognised risk factor for Alzheimer’s disease dementia, say researchers.

07-06-2016 | Alzheimer's disease | News | Article

Cerebral microbleeds warn of dementia risk

A high cerebral microbleed count increases an individual’s risk of cognitive deterioration and dementia, study results indicate.

17-05-2016 | Alzheimer's disease | News | Article

Memory test offers clue to pathological diagnosis in primary progressive aphasia

Patients with primary progressive aphasia show selective vulnerabilities in effortless learning and delayed retrieval of verbal information if their syndrome is related to Alzheimer’s disease rather than frontotemporal lobar degeneration, research indicates.

12-05-2016 | Alzheimer's disease | News | Article

Tau pathology closely tracks brain function during early AD

Tau tangles may be a better indicator of cognitive changes during Alzheimer’s disease progression than beta-amyloid deposition, researchers propose.

11-05-2016 | Stroke | News | Article

Dementia risk high after ICH

A large study shows that nearly a third of patients who survive an intracerebral haemorrhage will go on to develop dementia within 4 years.

09-05-2016 | Alzheimer's disease | News | Article

Depression course predicts dementia risk

Patients with late-life depression have an increased risk of dementia if their symptoms increase over time, whereas a single episode of depression, even if severe, does not carry a significant risk, study findings indicate.

27-04-2016 | Alzheimer's disease | News | Article

Anticholinergic medication use best avoided in older adults

Brain imaging techniques have shown negative effects of anticholinergic medications on brain metabolism and size in cognitively healthy adults, providing further insight into the increased risk of cognitive decline associated with these medications.

22-04-2016 | Alzheimer's disease | News | Article

UK research allays fears over dramatic increases in dementia incidence

Research conducted in the UK has found a 20% drop in the incidence of dementia over the past 2 decades, leading to an estimated 41,000 fewer cases per year in people aged 65 years and older than previously expected.

18-04-2016 | Alzheimer's disease | News | Article

MR may detect earliest Alzheimer’s brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer’s disease biomarkers, say researchers.

15-04-2016 | Alzheimer's disease | News | Article

Alzheimer’s preclinical staging criteria supported

The Alzheimer’s disease preclinical staging criteria proposed by the National Institute on Aging and the Alzheimer’s Association appear to be valid over more than a decade of follow-up, say researchers.

12-04-2016 | Alzheimer's disease | News | Article

Translational study identifies novel AD target

Cell surface heparan sulfates, which are found on all cells including neurons, have become the latest putative target to combat Alzheimer’s disease.

11-04-2016 | Neurology | News | Article

Prognostic markers expanded for AD, ALS

Two studies expand the range of putative prognostic markers for neurological disease, with creatinine kinase found to be prognostic in amyotrophic lateral sclerosis and neurogranin offering diagnostic and prognostic potential in Alzheimer’s disease.

17-03-2016 | Alzheimer's disease | Main feed | Article

Women’s verbal memory advantage may mask cognitive decline

Women with amnestic mild cognitive impairment have better verbal memory skills than their male counterparts during the early stages of hippocampal decline.

25-02-2016 | Alzheimer's disease | News | Article

Comorbid neuropathologies have major impact on cognition

Cognitive impairment is most likely to affect people with multiple types of brain pathology, irrespective of which particular pathologies they have, a study shows.

12-02-2016 | Alzheimer's disease | News | Article

Astrocytes implicated in preclinical AD

Astrocytes are activated in the brains of people with autosomal dominant Alzheimer’s disease long before symptoms appear and even before amyloidosis begins, a study shows.

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