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Rheumatology

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10-09-2019 | Rheumatology | News | Article

Support for TNF inhibitor–methotrexate combination in older RA patients

Rheumatoid arthritis patients aged 65 years or older experience a similar response to treatment with golimumab plus methotrexate compared with younger patients, suggests a post-hoc analysis of the GO-FURTHER trial.

10-09-2019 | Rheumatology | News | Article

FDA gives nod to ixekizumab for ankylosing spondylitis

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09-09-2019 | Rheumatology | News | Article

Nintedanib receives FDA approval for SSc-ILD

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09-09-2019 | Rheumatology | News | Article

Denosumab plus high-dose teriparatide may improve postmenopausal osteoporosis

Combining denosumab with high-dose rather than standard-dose teriparatide results in greater increases in spine and hip bone mineral density in postmenopausal women with osteoporosis, phase IV study data show.

06-09-2019 | Rheumatology | News | Article

Optimal warfarin treatment intensity for VTE prevention after arthroplasty remains unclear

Low-intensity warfarin treatment has not demonstrated noninferiority to standard-intensity warfarin for the prevention of venous thromboembolism among older people undergoing hip or knee replacement surgery in a randomized controlled trial.

06-09-2019 | Rheumatology | News | Article

Inadequate glycemic testing prior to joint replacement surgery

A substantial proportion of patients undergoing total joint replacement do not receive a test for glycemic control prior to surgery, researchers report.

05-09-2019 | Rheumatology | News | Article

Pregnancy outcomes largely unaffected by DMARD exposure at conception in JIA

Juvenile idiopathic arthritis patients taking DMARDs at the time they conceive do not have an increased risk for major adverse pregnancy outcomes, research suggests.

04-09-2019 | Rheumatology | Main feed | Article

Preliminary trial results support further investigation of low-dose IL-2 therapy for SLE

The low-dose recombinant human interleukin IL-2 therapy aldesleukin has a favorable safety profile and may restore regulatory T-cell homeostasis in people with systemic lupus erythematosus, suggest findings from a proof-of-concept phase I/IIa clinical trial.

03-09-2019 | Rheumatology | News | Article

EMA recommends new measures to avoid methotrexate dosing errors

The EMA has issued new precautions for the avoidance of dosing errors when using methotrexate for the treatment of inflammatory disorders such as rheumatoid arthritis and psoriasis.

02-09-2019 | Rheumatology | News | Article

Alcohol consumption linked to axSpA progression

Alcohol consumption may be a modifiable risk factor for spinal structural damage among patients with axial spondyloarthritis, researchers report.

30-08-2019 | Rheumatology | News | Article

Observational data support long-term adalimumab use in polyarticular JIA

Adalimumab, used with or without concurrent methotrexate, appears to be well tolerated among children with polyarticular‐course juvenile idiopathic arthritis, 7-year data from the STRIVE registry show.

30-08-2019 | Rheumatology | News | Article

Extension study demonstrates stable long-term safety, efficacy profiles for peficitinib

The Janus kinase inhibitor peficitinib has demonstrated a consistent safety and efficacy profile over 2 years of follow-up among Japanese patients with rheumatoid arthritis, researchers report.

29-08-2019 | Rheumatology | News | Article

TrkA inhibitor disappoints in knee osteoarthritis trial

medwireNews: The tropomyosin receptor kinase A (TrkA) inhibitor ASP7962 has failed to improve pain or physical function among patients with painful knee osteoarthritis in a phase II trial.

28-08-2019 | Rheumatology | News | Article

Multiple DMARD use may attenuate adalimumab response in RA

Previous exposure to multiple conventional DMARDs is associated with a blunted response to treatment with adalimumab plus methotrexate among patients with rheumatoid arthritis, indicate findings from a post-hoc analysis.

27-08-2019 | Rheumatology | News | Article

Meta-analysis questions use of osteoporosis treatments to reduce mortality risk

Findings from a meta-analysis published in JAMA Internal Medicine indicate that drug treatments for osteoporosis, particularly bisphosphonates, are not associated with a significant reduction in overall mortality risk.

23-08-2019 | Rheumatology | News | Article

US guidelines for the treatment of axSpA published

The ACR, Spondylitis Association of America, and Spondyloarthritis Research and Treatment Network have issued updated recommendations for the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis.

23-08-2019 | Rheumatology | News | Article

Antibiotic exposure may influence the odds of developing RA

Exposure to systemic oral antibiotics is associated with a higher risk for rheumatoid arthritis, a database analysis suggests.

22-08-2019 | Rheumatology | News | Article

Neutrophil biomarkers show promise for predicting RA prognosis

Neutrophil-derived biomarkers correlate with disease activity and can predict joint space narrowing and erosive disease among patients with rheumatoid arthritis, researchers report.

21-08-2019 | Rheumatology | News | Article

Upadacitinib gains FDA approval for RA

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21-08-2019 | Rheumatology | News | Article

EULAR updates vaccination guidance for patients with rheumatic diseases

EULAR has developed up-to-date guidelines for the use of vaccinations in patients with rheumatic diseases, based on a systematic literature review and expert opinion.

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