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Oncology

Latest articles

14-11-2019 | Oncology | News | Article

No delay in progressive CSPC metastasis with PAP-targeted vaccine

Phase II study data suggest that the prostatic acid phosphatase-encoding pTVG-HP vaccine does not improve metastasis-free survival in men with progressive, nonmetastatic, castration-sensitive prostate cancer.

13-11-2019 | Oncology | News | Article

HLA-I evolutionary divergence linked to ICI response in cancer

HLA class I evolutionary divergence is associated with response to immune checkpoint inhibitor treatment in people with cancer, show data published in Nature Medicine.

12-11-2019 | Oncology | News | Article

Lung cancer undertreatment common in USA, regardless of clinical subtype

Between 2010 and 2014, more than a third of lung cancer patients in the USA received less intensive treatment than recommended, or indeed no treatment at all, shows an analysis of data from the US National Cancer Database.

11-11-2019 | Oncology | News | Article

‘No justification’ for HIV exclusion from ICI trials

Researchers highlight the “almost universal exclusion” of people living with HIV from clinical trials of immune checkpoint inhibitor therapies despite malignancy being the leading cause of morbidity and mortality in this population.

08-11-2019 | Oncology | News | Article

Ensartinib could expand treatment options for ALK-positive NSCLC

At least half of patients with crizotinib-resistant ALK translocation-positive non-small-cell lung cancer respond to treatment with the new-generation ALK inhibitor ensartinib, including those with brain metastases, phase II study data show.

07-11-2019 | Diabetes | Highlight | Article

Detection bias may contribute to reduced prostate cancer risk in diabetes

The reduced prostate cancer risk seen in men with diabetes may be partly explained by detection bias due to a lower biopsy rate following an elevated prostate-specific antigen test result, population-based study data show.

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