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Rheumatology

Golimumab may reduce uveitis risk in patients with ankylosing spondylitis

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Findings from the real-world GO-EASY study suggest that treatment with the tumor necrosis factor inhibitor golimumab is associated with a significant reduction in the risk for acute anterior uveitis among patients with ankylosing spondylitis.

Neurology

Anticoagulants could stave off increased risk of dementia associated with AF

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Study findings show an increased risk of dementia in older people with atrial fibrillation and support the use of anticoagulants to reduce the likelihood.

Respiratory

Triple combination CFTR modulator therapy shows potential for cystic fibrosis

pills

Combination therapy with a next-generation cystic fibrosis transmembrane conductance regulator corrector, together with tezacaftor and ivacaftor, may be a promising treatment option for cystic fibrosis, suggest findings from two studies published in The New England Journal of Medicine.

Oncology

Neoadjuvant pembrolizumab ‘worthwhile’ for some invasive bladder cancers

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Neoadjuvant pembrolizumab therapy results in an “impressively high” pathologic complete response rate among patients with programmed cell death ligand 1-positive muscle-invasive bladder carcinoma, researchers say.

Headlines from across medwireNews

19-11-2018 | Rheumatology | News | Article

Autoantibody positivity linked to favorable treatment outcomes in RA patients

Among patients with rheumatoid arthritis, a combination of anticitrullinated protein antibody and rheumatoid factor positivity is associated with faster treatment response and a greater likelihood of achieving remission, researchers report.

19-11-2018 | Oncology | Main feed | News

Clinically important safety differences found among immune checkpoint inhibitors

A network meta-analysis has ranked the safety of immune checkpoint inhibitors in cancer treatment, with atezolizumab revealed to have the best general safety profile.

15-11-2018 | Rheumatology | News | Article

Intravenous, subcutaneous forms of tocilizumab similarly effective in RA patients

Real-world study results suggest that the subcutaneous and intravenous forms of tocilizumab are associated with similar effectiveness among patients with rheumatoid arthritis.

15-11-2018 | Chronic obstructive pulmonary disease | News | Article

BREATHE programme improves outcomes for COPD patients

An intervention combining transitional care and self-management support after hospital discharge reduces the number of subsequent hospital visits and improves health-related quality of life among patients with chronic obstructive pulmonary disease, trial findings indicate.

15-11-2018 | Alzheimer's disease | News | Article

CSF neurofilament light a ‘preferred’ biomarker for MCI progression

Elevated cerebrospinal fluid neurofilament light levels are associated with an increased risk of mild cognitive impairment, indicate findings from a population-based study.

15-11-2018 | Ophthalmology | News | Article

Current glaucoma staging systems underestimate disease severity

Current glaucoma staging systems based on 24-2 (or 30-2) visual fields underestimate disease severity and the presence of macular damage when compared with 10-2 visual fields and high-resolution macular imaging, US researchers report.

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