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Treatment cardiotoxicity reduction pays late dividends after childhood cancer

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Efforts to reduce the cardiotoxicity of cancer treatment in childhood appear to have paid dividends, report researchers.


Folic acid supplement recommendation for neural tube defects upheld

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The US Preventive Services Task Force has reaffirmed its 2009 recommendation that women who are planning or capable of pregnancy should take a daily supplement containing 400 µg to 800 µg of folic acid for the prevention of neural tube defects.


Tumor aneuploidy linked to immunotherapy response


US researchers suggest that tumor aneuploidy could be a useful marker for response to immune checkpoint blockade in patients with cancer.

Headlines from across medwireNews

20-01-2017 | Pulmonary hypertension | News | Article

Biological similarities between Cpc-PH and PAH identified

Research published in the Journal of the American College of Cardiology suggests that there could be a pathophysiological overlap between combined post-capillary and pre-capillary pulmonary hypertension and pulmonary arterial hypertension.

18-01-2017 | Colorectal cancer | News | Article

Serum LDH may predict metastatic CRC bevacizumab benefit after progression

Baseline levels of serum lactate dehydrogenase could help select the patients with metastatic colorectal cancer who are most likely to benefit from continuing bevacizumab after progressing on first-line therapy.

17-01-2017 | Leukaemia | News | Article

Venetoclax plus rituximab ‘attractive potential option’ for relapsed, refractory CLL

Venetoclax plus rituximab is active and well tolerated in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma, shows a phase Ib trial.

17-01-2017 | Interventional cardiology | News | Article

Early discharge feasible following percutaneous mitral valve repair

Early discharge from hospital is feasible in selected patients following percutaneous edge-to-edge mitral valve repair and is not associated with an increase in adverse events, researchers report.

17-01-2017 | Epilepsy | News | Article

Guideline advises on fMRI use for mapping brain function prior to epilepsy surgery

The American Academy of Neurology has recommended the use of functional magnetic resonance imaging as an alternative to the intracarotid amobarbital procedure for presurgical mapping of language and memory function in patients with epilepsy.

16-01-2017 | Acute coronary syndromes | News | Article

Left ventricular hypertrophy could increase tissue damage during STEMI

A substudy of the DANAMI-3 trial suggests that adverse outcomes associated with left ventricular hypertrophy among patients with ST-segment elevation myocardial infarction treated with percutaneous coronary intervention could be mediated by increased myocardial damage.

Beyond the news


medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

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Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.


Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

Click through to read research news from the conference.

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