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Rheumatology

Gout flares linked to temporary increase in cardiovascular risk

Gout flares are associated with an increased risk for cardiovascular events in the following 120 days, study findings suggest.

Oncology

ctDNA analysis can detect KRAS G12C mutations in people with cancer

A large US study has shown the feasibility of circulating tumor DNA analysis to detect KRAS G12C mutations in patients with solid tumors.

Headlines from across medwireNews

10-08-2022 | Oncology | News | Article

​​​​​​​Sub-lobar resection ‘new standard of care’ for small-sized NSCLC

Sub-lobar resection is noninferior to lobectomy with respect to disease-free survival and overall survival in patients with clinical stage T1a N0 non-small-cell lung cancer and tumors no larger than 2 cm, report the CALGB 140503 investigators.

09-08-2022 | Oncology | News | Article

NADIM II: Adding nivolumab to neoadjuvant chemo improves stage III NSCLC survival

The addition of nivolumab to neoadjuvant chemotherapy significantly improves the progression-free survival and overall survival of individuals with resectable stage IIIA–B non-small-cell lung cancer, suggest data from NADIM II.

09-08-2022 | Oncology | News | Article

​​​​​​​IMpower010 shows OS trend favoring adjuvant atezolizumab in certain NSCLC patients

Adjuvant treatment with atezolizumab is associated with a trend toward improved overall survival relative to best supportive care in people with resected stage II–IIIA non-small-cell lung cancer positive for PD-L1, indicate IMpower010 results.

09-08-2022 | Diabetes | News | Article

Lifestyle intervention strategy beneficial for older adults with diabetes

Lifestyle intervention proves “highly successful” in adults with diabetes aged 65 to 85 years, improving both metabolic and functional health, report researchers.

09-08-2022 | Rheumatology | News | Article

Substantial lifetime risk for axSpA among relatives of patients with ankylosing spondylitis

A 35-year follow-up study has identified a 27.1% lifetime recurrence rate of axial spondyloarthritis among first-degree relatives of patients with human leukocyte antigen HLA-B27-positive ankylosing spondylitis.

08-08-2022 | Diabetes | News | Article

Daily insulin dose may be linked to cancer risk in type 1 diabetes

People with type 1 diabetes who take a higher daily dose of insulin may have an increased risk for cancer compared with those on lower doses, US researchers report.

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