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Rheumatology

Golimumab may reduce uveitis risk in patients with ankylosing spondylitis

Eye exam

Findings from the real-world GO-EASY study suggest that treatment with the tumor necrosis factor inhibitor golimumab is associated with a significant reduction in the risk for acute anterior uveitis among patients with ankylosing spondylitis.

Neurology

Anticoagulants could stave off increased risk of dementia associated with AF

pills_bottle_spill

Study findings show an increased risk of dementia in older people with atrial fibrillation and support the use of anticoagulants to reduce the likelihood.

Respiratory

Triple combination CFTR modulator therapy shows potential for cystic fibrosis

pills

Combination therapy with a next-generation cystic fibrosis transmembrane conductance regulator corrector, together with tezacaftor and ivacaftor, may be a promising treatment option for cystic fibrosis, suggest findings from two studies published in The New England Journal of Medicine.

Oncology

Neoadjuvant pembrolizumab ‘worthwhile’ for some invasive bladder cancers

IV drip_patient's hand

Neoadjuvant pembrolizumab therapy results in an “impressively high” pathologic complete response rate among patients with programmed cell death ligand 1-positive muscle-invasive bladder carcinoma, researchers say.

Headlines from across medwireNews

13-11-2018 | Lung cancer | Main feed | News

Lorlatinib shows promising activity against ALK-positive advanced NSCLC

Patients with ALK-positive advanced non-small-cell lung cancer respond to the third-generation ALK and ROS1 tyrosine kinase inhibitor lorlatinib irrespective of previous ALK tyrosine kinase inhibitor treatment status, phase II study data show.

12-11-2018 | Rheumatology | News | Article

Further support for 3-month assessment to guide DMARD adjustment in RA patients

Measuring disease activity at 3 months can help predict DMARD response at 6 months in patients with rheumatoid arthritis, researchers report.

09-11-2018 | Rheumatology | News | Article

Activity tracking ‘feasible’ for adolescents with JIA

Findings from a pilot study indicate that activity tracking using a wrist-worn device is a feasible approach for promoting physical activity in adolescent patients with juvenile idiopathic arthritis

09-11-2018 | Prostate cancer | News | Article

Prostate cancer patients willing to make trade-offs between survival, side effects

Men with a new diagnosis of nonmetastatic prostate cancer say they would accept small reductions in survival odds if that meant fewer side effects and an improved quality of life, suggests the COMPARE study.

08-11-2018 | Ophthalmology | Main feed | News

Intravitreal injection linked to substantial temporary blood pressure increase

Patients undergoing intravitreal injections with anti–vascular endothelial growth factor agents can experience substantial transient increases in systolic blood pressure, Swiss researchers report.

08-11-2018 | Neurology | Main feed | News

Global burden of motor neuron diseases quantified

High-income countries currently have the highest rates of motor neuron diseases worldwide, and the burden is increasing with the ageing population, shows an analysis of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016.

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