medwireNews

The presence of the BRAF V600E mutation in colorectal liver metastases is associated with a worse prognosis and increased risk for recurrence, according to findings from an international retrospective cohort study.

Results of a systematic review and meta-analysis suggest that a substantial proportion of patients with chronic inflammatory arthritis have concomitant fibromyalgia, which may influence measures of disease activity.

Preliminary results suggest a role for the combination of the CTLA-4 inhibitor tremelimumab and the PD-L1 blocker durvalumab in the treatment of inoperable pleural or peritoneal mesothelioma.

A predictive model including baseline disease activity score, smoking status, and alcohol consumption may help to identify which patients with rheumatoid arthritis are likely to have a poor response to methotrexate-based treatment, researchers report.

Radionuclide treatment with lutetium-177-prostate-specific membrane antigen-617 shows potential for men with metastatic castration-resistant prostate cancer that has progressed after standard therapy, researchers report.

Results of a randomized controlled trial suggest that an internet-based self-management program is no more beneficial than an educational book for patients with systemic sclerosis.