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Cardiology

Diet associated with ‘substantial proportion’ of cardiometabolic deaths

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Research published in JAMA suggests that suboptimal intake of specific dietary factors is associated with almost half of deaths from heart disease, stroke, or type 2 diabetes in the USA.

Neurology

Migraine linked to spontaneous cervical artery dissection

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IPSYS investigators have found a significant association between migraine and cervical artery dissection, identifying it as a potential biomarker.

Oncology

Surgical resection still important in abdominal melanoma metastases

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Patients who undergo surgical resection of abdominal visceral melanoma metastases have significantly better overall survival than those who do not, and the outcome is not greatly improved by modern systemic treatments, study findings indicate.

Headlines from across medwireNews

24-04-2017 | Oncology | News | Article

Survival comparable with bladder-sparing trimodal therapy and radical cystectomy

A propensity score-matched cohort analysis finds no significant difference between bladder-sparing trimodal therapy and radical cystectomy with respect to survival in patients with muscle-invasive bladder cancer.

24-04-2017 | Rheumatology | News | Article

Infection risk with TNF inhibitors confirmed in juvenile idiopathic arthritis

Study results suggest that tumor necrosis factor-alpha inhibitors are associated with a higher risk for serious infection than disease-modifying antirheumatic drugs among children with juvenile idiopathic arthritis.

21-04-2017 | Rheumatology | News | Article

Support for mycophenolate therapy in patients with SSc-related interstitial lung disease

Mycophenolate mofetil is associated with improvements in lung function compared with placebo among patients with systemic sclerosis (SSc)-associated interstitial lung disease, study results suggest.

21-04-2017 | Oncology | News | Article

Caution needed when using PFS as an OS surrogate in immunotherapy trials

In phase II and III trials of oncologic immunotherapeutic agents, treatment effect sizes are on average larger for progression-free survival than for overall survival, find researchers who question the value of using progression-free survival as a surrogate for overall survival in such trials.

20-04-2017 | Rheumatology | News | Article

Tocilizumab efficacy maintained for up to 2 years in RA patients

Patients with early rheumatoid arthritis who are treated with tocilizumab maintain the clinical benefits during their second year of treatment, analysis of phase III study data suggests.

19-04-2017 | Chronic myeloid leukaemia | News | Article

First-line generic imatinib offers ‘suboptimal efficacy’

For patients undergoing front-line treatment for chronic myeloid leukemia, generic treatment may be less effective than the branded agent, researchers suggest, but treatment efficacy is maintained in patients who switch from a branded to a generic formulation.

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medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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