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Local ablative therapy–pembrolizumab benefit suggested for metastatic NSCLC

Lung cancer illustration

Data from two phase II studies published in JAMA Oncology lend support to the sequential use of local ablative therapy and PD-1 blockade in patients with metastatic non-small-cell lung cancer.


Monocyte counts could predict IPF outcome


Elevated monocyte counts are associated with poor outcomes among patients with idiopathic pulmonary fibrosis, suggest study findings published in The Lancet Respiratory Medicine.


Partial knee replacement recommended for medial compartment osteoarthritis

Knee arthroplasty concept image (symbolic image with model)

Partial knee replacement is more cost-effective than total knee replacement over 5 years for patients with late-stage isolated medial compartment osteoarthritis of the knee, show results of the TOPKAT trial published in The Lancet.

Headlines from across medwireNews

23-07-2019 | Diabetes | News | Article

Medtronic closed-loop system with bolus correction promising in first clinical trial

The latest iteration to the Medtronic artificial pancreas system, which includes automated correction boluses, shows promising results in its first home-based trial.

23-07-2019 | Oncology | News | Article

Nomogram-predicted recurrence risk may aid adjuvant chemotherapy stratification in MIBC

Muscle-invasive bladder cancer patients with a nomogram-derived 1-year recurrence probability of at least 40% are likely to benefit from adjuvant chemotherapy, suggests a retrospective study.

23-07-2019 | Rheumatology | News | Article

Low IGF1 levels predict CV risk in RA patients

Low levels of insulin-like growth factor 1 are associated with increased rates of cardiovascular events among women with rheumatoid arthritis, researchers report.

22-07-2019 | Diabetes | News | Article

Children with type 1 diabetes fare worse than peers in health, education

Children with type 1 diabetes have worse health outcomes and are more likely to miss school and have special educational needs than their nondiabetic peers, show results of a large study conducted in Scotland.

19-07-2019 | Rheumatology | News | Article

Genetic loci influencing asymptomatic hyperuricemia to gout progression identified

A Japanese genome-wide association study has identified novel genetic loci associated with the susceptibility of gout in individuals with asymptomatic hyperuricemia.

19-07-2019 | Oncology | News | Article

NCCN releases guidance for bladder cancer patients

The National Comprehensive Cancer Network has issued patient-oriented guidelines to help individuals with bladder cancer better understand and manage their condition.

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