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Asthma

Sex, obesity, and immune disturbances inform severe asthma phenotype in later life

Bathroom scales_feet

With advancing age, asthma becomes more prevalent in women than men and is associated with obesity, greater airflow limitation, and lower markers of T-helper cell type 2 inflammation, study findings show.

HBV

Consensus reached on design of clinical trials for novel, curative HBV therapies

Discussion group

A panel of hepatitis B virus experts has issued a consensus statement intended to aid in standardizing the efficacy and safety appraisals of novel, potentially curative antiviral and immune modulatory agents.

Oncology

Long-term breast cancer recurrence risk linked to original TN status

Mammography result

The risk for breast cancer recurrence increases at a steady rate for at least 15 years after the end of planned endocrine therapy and is strongly associated with the original tumor diameter and nodal status, meta-analysis data show.

Rheumatology

Personalized RA risk guidance may motivate healthy lifestyle changes

DNA_chromosomes

Results of a proof-of-concept trial suggest that providing personalized information about rheumatoid arthritis risk using an online tool could motivate people to improve their health behaviors.

Headlines from across medwireNews

17-11-2017 | Rheumatology | News | Article

Online self-management program boosts JIA HRQoL

An internet-based educational tool developed by Canadian researchers helps adolescents with juvenile idiopathic arthritis to manage their disease and leads to improvements in their health-related quality of life relative to standard disease education.

17-11-2017 | Oncology | News | Article

Dasatinib receives pediatric CML go-ahead

Read more on this US FDA approval here

16-11-2017 | Colorectal cancer | News | Article

Mismatch repair deficiency testing underused for CRC patients in USA

Researchers have warned that underuse of mismatch repair deficiency testing “is a persistent and pervasive problem” in the USA, even among young adults with colorectal cancer where its use is unequivocally recommended.

16-11-2017 | Rheumatology | News | Article

Exploring RA treatment patterns

Several studies presented at the 2017 ACR/ARHP Annual Meeting in San Diego, California, USA, explored different aspects of rheumatoid arthritis treatment, including guideline recommendations, adherence to second-line therapy, and predicting treatment response.

15-11-2017 | Rheumatology | News | Article

Extended benefits of ixekizumab treatment in patients with PsA

Results from the extension phase of the SPIRIT-P2 trial suggest that the benefits of treatment with ixekizumab are maintained for up to 1 year among patients with psoriatic arthritis.

15-11-2017 | Oncology | News | Article

No survival benefit with olaparib plus paclitaxel in advanced gastric cancer

Adding olaparib to paclitaxel does not improve survival among Asian patients with advanced gastric cancer that has progressed during or after first-line therapy, show results of the phase III GOLD trial.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

Interested in paediatric endocrinology?

Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.

medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

Click through to read research news from the conference.

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