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Asthma

Sex, obesity, and immune disturbances inform severe asthma phenotype in later life

Bathroom scales_feet

With advancing age, asthma becomes more prevalent in women than men and is associated with obesity, greater airflow limitation, and lower markers of T-helper cell type 2 inflammation, study findings show.

HBV

Consensus reached on design of clinical trials for novel, curative HBV therapies

Discussion group

A panel of hepatitis B virus experts has issued a consensus statement intended to aid in standardizing the efficacy and safety appraisals of novel, potentially curative antiviral and immune modulatory agents.

Oncology

Contemporary hormonal contraceptives not free from breast cancer risk

IUD and pills

A Danish population-based study shows that women who are current or recent users of contemporary hormonal contraceptives have an elevated risk for developing breast cancer relative to those who have never used such measures, but the absolute increase in risk remains small.

Rheumatology

Postpartum follow-up of women with JIA warranted

Pregnant lady with doctor

The majority of women with juvenile idiopathic arthritis maintain stable disease activity during and after pregnancy, but some patients experience a small increase in disease activity following childbirth, research suggests.

Headlines from across medwireNews

15-12-2017 | HBV | News | Article

Durability of HBsAg clearance induced by NA therapy demonstrated

Clearance of hepatitis B surface antigen with nucleos(t)ide analogs is as durable as spontaneous clearance in patients with chronic hepatitis B virus infection, researchers report.

15-12-2017 | HBV | News | Article

HBV remains major contributor to primary liver cancer globally

Hepatitis B virus infection is the leading cause of incident primary liver cancer and associated mortality worldwide, according to research published in JAMA Oncology.

15-12-2017 | Prostate cancer | News | Article

Enzalutamide may not be contraindicated for mCRPC patients with seizure risk factors

In men with metastatic castration-resistant prostate cancer and seizure risk factors, treatment with enzalutamide does not increase the incidence of seizures, shows the UPWARD safety study.

15-12-2017 | Rheumatology | News | Article

Severe weight loss in early RA linked to increased mortality risk

Women with rheumatoid arthritis who experience severe weight loss early in the disease course have a higher risk for subsequent mortality than those who maintain a stable weight, researchers report.

14-12-2017 | Rheumatology | News | Article

Femoral neck may be optimal site for measuring bone loss in AS patients

Study results suggest that bone mineral density changes over time among patients with ankylosing spondylitis, and that the femoral neck may be the best site to measure bone loss.

14-12-2017 | Breast cancer | News | Article

Short-term GnRHa therapy may prevent breast cancer chemotherapy-related ovarian dysfunction

Temporary ovarian suppression with a gonadotropin-releasing hormone analog alongside neoadjuvant or adjuvant chemotherapy could help preserve ovarian function and fertility in premenopausal women with early-stage breast cancer, shows a pooled analysis.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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