Editors' picks

Asthma

Eosinophilia linked to lung function decline irrespective of asthma symptoms

High blood eosinophil counts are associated with airflow obstruction and lung function decline in patients with asthma, but also in people without respiratory symptoms, population-based study findings show.

HBV

Updated AASLD guidance released on HBV prevention, diagnosis, and treatment

The American Association for the Study of Liver Diseases has issued a guidance statement for chronic hepatitis B virus, covering topics ranging from screening and prevention through to the clinical management of patients.

Oncology

Cancer immunotherapy efficacy may vary by sex

The magnitude of the survival benefit associated with immune checkpoint inhibitor treatment appears to be sex dependent, with women benefiting less than men, according to a meta-analysis published in The Lancet Oncology.

Rheumatology

Diclofenac linked to increased myocardial infarction risk in SpA patients

Current use of the nonsteroidal anti-inflammatory drug diclofenac, but not of naproxen, is associated with a threefold increased risk for myocardial infarction among individuals with spondyloarthritis, according to recent findings.

Headlines from across medwireNews

21-05-2018 | Lymphoma | News | Article

First-line rituximab plus GemOx promising in older patients with DLBCL

The combination of rituximab, gemcitabine, and oxaliplatin has potential for the treatment of older patients with a new diagnosis of diffuse large B-cell lymphoma, suggests a Chinese phase II trial.

21-05-2018 | Rheumatology | News | Article

Recommendations issued for managing pain in patients with arthritis

EULAR has published recommendations for pain management in patients with inflammatory arthritis and osteoarthritis.

21-05-2018 | Oncology | News | Article

Epoetin alfa biosimilar approved for chemotherapy-related anemia

Click through for more on this US FDA announcement

18-05-2018 | Rheumatology | News | Article

HBV infection may compromise treatment response in patients with RA

Chronic hepatitis B virus infection is associated with poor response to treatment among patients with rheumatoid arthritis, study results suggest.

18-05-2018 | Gastrointestinal cancer | News | Article

Neoadjuvant therapy for pancreatic cancer induces positive changes in body composition

Patients with borderline resectable or locally advanced pancreatic cancer experience a significant loss of adipose tissue along with an increase in muscle mass during neoadjuvant therapy that may improve the odds for resection, researchers report.

17-05-2018 | Rheumatology | News | Article

Durable response to sarilumab in patients with RA

Sarilumab has consistent safety and efficacy profiles over 2 years among patients with moderate-to-severe rheumatoid arthritis and an inadequate response to methotrexate, results of an open-label extension study suggest.

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Blood sample/© Shawn Hempel / stock.adobe.com, Folder_Binders in background/© Bacho Foto / Fotolia, Male & female symbols/© seraficus / Getty Images / iStock, Heartbeat/© BrianAJackson / Getty Images /, Children with medical team/© Christopher Futcher, Lucy Piper, Lynda Williams, Eleanor McDermid, Shreeya Nanda, Claire Barnard, Alison Chapman, Kamran Ahmad