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Asthma

Eosinophilia linked to lung function decline irrespective of asthma symptoms

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High blood eosinophil counts are associated with airflow obstruction and lung function decline in patients with asthma, but also in people without respiratory symptoms, population-based study findings show.

HBV

Updated AASLD guidance released on HBV prevention, diagnosis, and treatment

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The American Association for the Study of Liver Diseases has issued a guidance statement for chronic hepatitis B virus, covering topics ranging from screening and prevention through to the clinical management of patients.

Oncology

Cancer immunotherapy efficacy may vary by sex

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The magnitude of the survival benefit associated with immune checkpoint inhibitor treatment appears to be sex dependent, with women benefiting less than men, according to a meta-analysis published in The Lancet Oncology.

Rheumatology

Diclofenac linked to increased myocardial infarction risk in SpA patients

Heartbeat

Current use of the nonsteroidal anti-inflammatory drug diclofenac, but not of naproxen, is associated with a threefold increased risk for myocardial infarction among individuals with spondyloarthritis, according to recent findings.

Headlines from across medwireNews

21-05-2018 | Lymphoma | News | Article

First-line rituximab plus GemOx promising in older patients with DLBCL

The combination of rituximab, gemcitabine, and oxaliplatin has potential for the treatment of older patients with a new diagnosis of diffuse large B-cell lymphoma, suggests a Chinese phase II trial.

21-05-2018 | Rheumatology | News | Article

Recommendations issued for managing pain in patients with arthritis

EULAR has published recommendations for pain management in patients with inflammatory arthritis and osteoarthritis.

21-05-2018 | Oncology | News | Article

Epoetin alfa biosimilar approved for chemotherapy-related anemia

Click through for more on this US FDA announcement

18-05-2018 | Rheumatology | News | Article

HBV infection may compromise treatment response in patients with RA

Chronic hepatitis B virus infection is associated with poor response to treatment among patients with rheumatoid arthritis, study results suggest.

18-05-2018 | Gastrointestinal cancer | News | Article

Neoadjuvant therapy for pancreatic cancer induces positive changes in body composition

Patients with borderline resectable or locally advanced pancreatic cancer experience a significant loss of adipose tissue along with an increase in muscle mass during neoadjuvant therapy that may improve the odds for resection, researchers report.

17-05-2018 | Rheumatology | News | Article

Durable response to sarilumab in patients with RA

Sarilumab has consistent safety and efficacy profiles over 2 years among patients with moderate-to-severe rheumatoid arthritis and an inadequate response to methotrexate, results of an open-label extension study suggest.

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