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Cardiology

Beta blockers still essential in reperfusion era

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Early use of β blockers is still important in myocardial infarction patients without heart failure in the reperfusion era, a study suggests.

Diabetes

FTO gene has no influence on weight loss intervention success

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Overweight and obese people who carry two minor alleles of the fat mass and obesity associated gene respond just as well to weight loss interventions as noncarriers, shows a meta-analysis of individual participant data.

Neurology

Factors linked to stroke undertreatment identified

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An analysis of the US Get With The Guidelines–Stroke registry has revealed multiple patient and hospital characteristics associated with failure to provide intravenous tissue plasminogen activator therapy in eligible patients with acute ischaemic stroke.

Oncology

ProtecT clinical, patient-reported outcomes revealed

Three arrows

Two articles published in The New England Journal of Medicine report on the clinical and patient-reported outcomes of the ProtecT trial’s assessment of three approaches for the management of localised prostate cancer detected by prostate-specific antigen testing.

Headlines from across medwireNews

27-09-2016 | Stroke | News | Article

Speed is key for stroke thrombectomy

Early initiation of endovascular stroke treatment is critical to give patients the best chance of achieving functional independence, say the HERMES collaborators.

27-09-2016 | Cardiometabolic | News | Article

Statin, some nonstatin lipid-lowering therapies broadly equivalent

Nonstatin therapies that act via upregulation of the low-density lipoprotein receptor prevent major vascular events as effectively as statins do, shows an analysis in JAMA.

27-09-2016 | Epilepsy | News | Article

Reserve urged when using therapeutic coma in SE treatment

Therapeutic coma should be reserved for severe refractory convulsive status epilepticus after adequate and early dosing of first- and second-line drugs in line with current recommendations, say researchers.

27-09-2016 | Head and neck cancer | News | Article

Dalantercept monotherapy fails in refractory, metastatic SCCHN

A phase II trial of single-agent dalantercept in patients with platinum-refractory, recurrent or metastatic squamous cell carcinoma of the head and neck has failed to meet its primary efficacy endpoint, a US research team reports.

26-09-2016 | Oncology | News | Article

Select HCC patients may benefit from second-line ramucirumab

Chronic liver disease severity and pretreatment α-fetoprotein levels could help to identify hepatocellular carcinoma patients who may benefit from second-line treatment with ramucirumab, suggests an exploratory analysis of the REACH trial.

23-09-2016 | Oncology | News | Article

Prognostic value of MRD status in multiple myeloma confirmed

Post-treatment minimal residual disease status can serve as a marker of long-term survival in patients with newly diagnosed multiple myeloma, shows a meta-analysis.

Beyond the news

medwireNews@ECC2015

medwireNews brings you coverage of the 2015 European Cancer Congress, held in Vienna, Austria.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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