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Asthma

Sex, obesity, and immune disturbances inform severe asthma phenotype in later life

Bathroom scales_feet

With advancing age, asthma becomes more prevalent in women than men and is associated with obesity, greater airflow limitation, and lower markers of T-helper cell type 2 inflammation, study findings show.

HBV

Consensus reached on design of clinical trials for novel, curative HBV therapies

Discussion group

A panel of hepatitis B virus experts has issued a consensus statement intended to aid in standardizing the efficacy and safety appraisals of novel, potentially curative antiviral and immune modulatory agents.

Oncology

Benefit of breast cancer screening questioned in the Netherlands

Mammography

Data from the Netherlands adds to evidence suggesting that that a national breast cancer screening program has minimal impact on reducing breast cancer mortality but leads to considerable overdiagnosis of early-stage breast tumors.

Rheumatology

Arthritis prevalence in USA far higher than previously estimated

USA

An estimate of the number of individuals affected by arthritis in the USA, based on an expansive surveillance definition, has found a prevalence that is substantially higher than previously reported.

Headlines from across medwireNews

14-12-2017 | Rheumatology | News | Article

Femoral neck may be optimal site for measuring bone loss in AS patients

Study results suggest that bone mineral density changes over time among patients with ankylosing spondylitis, and that the femoral neck may be the best site to measure bone loss.

14-12-2017 | Breast cancer | News | Article

Short-term GnRHa therapy may prevent breast cancer chemotherapy-related ovarian dysfunction

Temporary ovarian suppression with a gonadotropin-releasing hormone analog alongside neoadjuvant or adjuvant chemotherapy could help preserve ovarian function and fertility in premenopausal women with early-stage breast cancer, shows a pooled analysis.

13-12-2017 | Oncology | News | Article

Edoxaban matches dalteparin performance for cancer-associated VTE

The oral factor Xa inhibitor edoxaban is as good as subcutaneous dalteparin for the prevention of recurrent venous thromboembolism or major bleeding in patients with cancer, show results of the Hokusai VTE cancer trial.

13-12-2017 | Rheumatology | News | Article

Postpartum follow-up of women with JIA warranted

The majority of women with juvenile idiopathic arthritis maintain stable disease activity during and after pregnancy, but some patients experience a small increase in disease activity following childbirth, research suggests.

12-12-2017 | Lymphoma | News | Article

Brentuximab vedotin may improve outcome in advanced Hodgkin lymphoma

A treatment regimen incorporating the anti-CD30 antibody–drug conjugate brentuximab vedotin is more effective than standard therapy with doxorubicin, bleomycin, vinblastine, and dacarbazine when used as a frontline therapy in patients with advanced Hodgkin lymphoma, phase III trial data show.

12-12-2017 | Rheumatology | News | Article

Further support for maintaining a healthy weight in RA patients

Overweight and obese patients with rheumatoid arthritis have lower rates of sustained remission than their normal-weight counterparts, researchers report.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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