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Asthma

Many patients fail to achieve good asthma control despite stepped treatment optimization

Asthma attack_woman

Stepped increases to optimize treatment improve asthma control, but for many patients optimal control still remains elusive, suggest findings from the real-life COAS study.

Cardiology

Diet associated with ‘substantial proportion’ of cardiometabolic deaths

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Research published in JAMA suggests that suboptimal intake of specific dietary factors is associated with almost half of deaths from heart disease, stroke, or type 2 diabetes in the USA.

Neurology

Migraine linked to spontaneous cervical artery dissection

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IPSYS investigators have found a significant association between migraine and cervical artery dissection, identifying it as a potential biomarker.

Oncology

Pegylated arginine deiminase acts against ASS1-deficient thoracic tumors

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Phase I trial data show that pegylated arginine deiminase is well tolerated, with a high response rate, when used in combination with cisplatin and pemetrexed to treat patients with argininosuccinate synthetase 1-deficient thoracic cancers.

Headlines from across medwireNews

27-04-2017 | Rheumatology | News | Article

Adalimumab shows promise in JIA-associated uveitis

Trial results published in The New England Journal of Medicine suggest that adding adalimumab to methotrexate treatment enhances the control of inflammation and reduces the rate of treatment failure among children and adolescents with juvenile idiopathic arthritis-associated uveitis.

26-04-2017 | Rheumatology | News | Article

Early RA treatment associated with lasting gains

Patients with rheumatoid arthritis who receive early treatment with disease-modifying antirheumatic drugs or steroids continue to experience therapeutic benefits up to 20 years later, researchers report.

26-04-2017 | Oncology | News | Article

Chemotherapy-induced nausea and vomiting risk predicted before each cycle

A model that incorporates eight readily available risk factors accurately predicts a patient’s likelihood for experiencing grade 2 or above chemotherapy-induced nausea and vomiting on a cycle-by-cycle basis, researchers report.

25-04-2017 | Neuro-oncology | News | Article

Glioblastoma survival benefit with vaccination, chemotherapy combination

Treatment with a cytomegalovirus-targeted dendritic cell-based vaccine together with dose-intensified temozolomide leads to improved survival in patients with newly diagnosed glioblastoma relative to historic controls given standard therapy, findings indicate.

24-04-2017 | Oncology | News | Article

Survival comparable with bladder-sparing trimodal therapy and radical cystectomy

A propensity score-matched cohort analysis finds no significant difference between bladder-sparing trimodal therapy and radical cystectomy with respect to survival in patients with muscle-invasive bladder cancer.

24-04-2017 | Rheumatology | News | Article

Infection risk with TNF inhibitors confirmed in juvenile idiopathic arthritis

Study results suggest that tumor necrosis factor-alpha inhibitors are associated with a higher risk for serious infection than disease-modifying antirheumatic drugs among children with juvenile idiopathic arthritis.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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