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Rheumatology

VROOM trial: Pausing methotrexate doubles antibody response to COVID-19 booster vaccine

Holding methotrexate treatment for 2 weeks following administration of a booster dose of vaccines against SARS-CoV-2 significantly improves the humoral immune response to vaccination, suggest findings from a randomized controlled trial.

Oncology

Real-world data magnify abemaciclib–thrombosis link in breast cancer

The incidence of thrombosis among people receiving the CDK4/6 inhibitor abemaciclib for metastatic breast cancer is approximately threefold higher in a real-world setting than that observed in clinical trials, US study data show.

Headlines from across medwireNews

06-07-2022 | Diabetes | News | Article

Hybrid closed-loop system brings benefits even with lax bolusing

Use of the Tandem Control IQ hybrid closed-loop insulin delivery system improves time in range even for users who very rarely bolus for meals or to treat hyperglycemia, an observational study suggests.

05-07-2022 | Diabetes | News | Article

Highest CV risk may warrant SGLT2 inhibitor rather than GLP-1 receptor agonist

The rate of heart failure hospitalization rises more than the rate of major adverse cardiovascular events as vascular risk increases in people with type 2 diabetes, report researchers.

05-07-2022 | Rheumatology | News | Article

EMA recommends approval of upadacitinib for nonradiographic axSpA

Click through for more information on this expanded indication

04-07-2022 | Oncology | News | Article

ASCO updates multiple advanced breast cancer guidelines

More information about the three updated clinical practice guidelines here.

04-07-2022 | Rheumatology | News | Article

Ozoralizumab shows promise in methotrexate-resistant RA

The next-generation anti-tumor necrosis factor-alpha antibody ozoralizumab significantly improves clinical signs and symptoms of rheumatoid arthritis relative to placebo in people with active disease despite methotrexate therapy, research suggests.

01-07-2022 | Diabetes | News | Article

Flash monitoring initiation may boost mental health

An observational study suggests that initiating flash glucose monitoring might lead to a reduction in symptoms of depression in people with insulin-treated diabetes.

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