Editors' picks

Asthma

Multivariate model predicts eosinophilic asthma without sputum induction

Researchers have designed a multivariate prediction model for identifying eosinophilic asthma that uses the activation state of peripheral blood eosinophils rather than sputum analysis.

HBV

HBV suppresses hepatic innate immune response

The host hepatic innate immune response is downregulated in untreated patients with chronic hepatitis B virus infection, shows a gene expression analysis.

Oncology

Selumetinib adds no benefit to docetaxel in KRAS-mutant advanced NSCLC

Adding selumetinib to docetaxel does not improve progression-free survival over docetaxel alone in patients with previously treated, advanced, KRAS-mutant non-small-cell lung cancer, phase III trial data show.

Rheumatology

Intra-articular steroid injections not supported for knee OA

Results of a randomized trial suggest no clinical benefits of triamcinolone injections for patients with symptomatic knee osteoarthritis.

Headlines from across medwireNews

24-05-2017 | Rheumatology | News | Article

Tocilizumab approved for giant cell arteritis

Click through to read more on this announcement

24-05-2017 | Gynaecological cancer | News | Article

Bevacizumab benefits ovarian cancer patients irrespective of timing

Patients with platinum-resistant ovarian cancer gain significant survival benefit from treatment with bevacizumab, regardless of whether its given with or after chemotherapy, an exploratory analysis of AURELIA study data show.

23-05-2017 | Rheumatology | News | Article

Support for switching from infliximab to biosimilar CT-P13

Results of two independent studies suggest that patients with inflammatory arthritis can be switched from infliximab to the biosimilar CT-P13 without compromising the effectiveness of treatment.

23-05-2017 | Head and neck cancer | News | Article

Recommendation against routine thyroid cancer screening retained

In a statement published in JAMA, the US Preventive Services Task Force upholds its 1996 recommendation against screening for thyroid cancer among asymptomatic adults.

22-05-2017 | Oncology | News | Article

Targeting mitochondrial metabolism shows promise in pancreatic cancer

Researchers report promising results from a phase I trial evaluating CPI-613, which targets mitochondrial metabolism, in combination with modified FOLFIRINOX chemotherapy for the treatment of metastatic pancreatic cancer.

22-05-2017 | Rheumatology | News | Article

Certolizumab efficacy for axial spondyloarthritis sustained over 4 years

The benefits of certolizumab pegol treatment in patients with axial spondyloarthritis are maintained over 4 years without worsening tolerability, researchers report.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

Interested in paediatric endocrinology?

Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.

medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

Click through to read research news from the conference.

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image credits

Blood sample/© Shawn Hempel / stock.adobe.com, DNA background/© Leigh Prather / Fotolia, lung_cancer2, Old man_holding knee/© [M] jxfzsy / Getty Images / iStock, ESMO 2016 flags_enhanced/© Lynda Williams, Children with medical team/© Christopher Futcher, Brandenburg Gate/© Nikada/iStock, Lucy Piper, Lynda Williams, Eleanor McDermid, Shreeya Nanda, Claire Barnard, Alison Chapman, Kamran Ahmad