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Inferior long-term survival with endovascular versus open repair of abdominal aortic aneurysm


Results from the EVAR trial 1 suggest that patients have poorer survival beyond 8 years after endovascular aneurysm repair compared with open repair, despite an early survival benefit.


Closed-loop gastric stimulation on a par with gastric band

Weight loss

Closed-loop gastric electrical stimulation is noninferior to adjustable gastric band for weight loss and has markedly fewer adverse effects, show the 1-year findings of a randomised trial.


MS drug may reduce not just slow disability symptoms

IV drip 2

Alemtuzumab improves pre-existing disability in multiple sclerosis patients rather than just slowing its progression, shows analysis of the CARE-MS II trial.


KEYNOTE-024 demonstrates pembrolizumab superiority for PD-L1-positive NSCLC


Pembrolizumab is superior to platinum-based chemotherapy for the first-line treatment of advanced non-small-cell lung cancer expressing programmed death-ligand 1 in at least 50% of cells, KEYNOTE-024 results show.

Headlines from across medwireNews

21-10-2016 | Diabetes | News | Article

GLP-1 analogues unlikely to raise breast cancer risk

A study of women with Type 2 diabetes in the UK Clinical Practice Research Datalink suggests that use of glucagon-like peptide-1 analogues is unlikely to raise their risk of breast cancer – at least relative to the use of dipeptidylpeptidase-4 inhibitors.

21-10-2016 | HBV | News | Article

HBV variants limit NA therapy response

Detectable baseline mutations in the basal core promoter and/or precore regions of hepatitis B virus are associated with a reduced likelihood of hepatitis B surface antigen loss during long-term nucleos(t)ide analogue treatment, suggest researchers.

21-10-2016 | Interventional cardiology | News | Article

TAVR risk prediction models validated

Researchers have validated the ability of four models to predict poor outcome up to 1 year after transcatheter aortic valve replacement using an external dataset.

20-10-2016 | Interventional cardiology | News | Article

Benefit of long-term antiplatelet therapy limited to complex PCI

The optimal duration of dual antiplatelet therapy following percutaneous coronary intervention could depend on procedural complexity, study results suggest.

19-10-2016 | Interventional cardiology | News | Article

Major adverse cardiac events risk low after new-generation stent implantation

A meta-analysis designed to compare hard outcomes after intravascular ultrasound- versus angiography-guided stent implantation highlights the very low risk of major adverse cardiac events among patients receiving new-generation drug-eluting stents.

19-10-2016 | Kidney cancer | News | Article

Cabozantinib ‘potential first-line option’ for advanced RCC

Cabozantinib significantly improves progression-free survival in newly diagnosed patients with intermediate- or poor-risk metastatic renal cell carcinoma, shows a head-to-head comparison with the standard of care sunitinib.

Beyond the news


medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

Click through to read the full reports of the latest research.

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Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.


Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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