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Asthma

Obesity impacts eosinophilia biomarker sensitivity

Bathroom scales_feet

Markers of inflammation conventionally used to identify eosinophilic airway inflammation in patients with asthma may not be effective in obese individuals, research suggests.

HBV

Maternal HBV infection raises preterm birth risk

Pregnant woman_grey background

Women with hepatitis B virus infection prior to becoming pregnant are significantly more likely to have a preterm birth than those without HBV, shows an analysis of a Chinese population-based cohort.

Oncology

Final BRIM-3 data confirm vemurafenib survival benefit over dacarbazine

melanoma_skin cancer

Final data from the BRIM-3 trial show that overall survival remains significantly better with vemurafenib than with dacarbazine when given to treatment-naïve patients with BRAFV600 mutation–positive metastatic melanoma.

Rheumatology

Finger prick test has potential to monitor adalimumab response

Finger prick test

Patients with inflammatory arthritis who are treated with adalimumab could monitor their blood levels of the drug using a finger prick test in place of full intravenous blood draws, researchers report.

Headlines from across medwireNews

18-08-2017 | Rheumatology | News | Article

Hopes revived for CD40L blockade in SLE

Phase I trial results suggest that the CD40 ligand inhibitor dapirolizumab pegol is well tolerated and elicits a clinical response in patients with systemic lupus erythematosus.

18-08-2017 | Oncology | News | Article

Azithromycin may increase post-HSCT hematologic malignancy relapse

A study investigating whether azithromycin improves airflow decline–free survival following allogeneic hematopoietic stem cell transplantation was terminated early due to an unexpected increased risk for hematologic malignancy relapse, researchers report.

17-08-2017 | Oncology | News | Article

Multiple orphan medications get nod from EMA

More details on these decisions available here

17-08-2017 | Oncology | News | Article

Opioid use common in cancer survivors

A Canadian population-based study shows higher prescribing rates for opioids among cancer survivors than in individuals without a prior cancer diagnosis.

16-08-2017 | Oncology | News | Article

Low vitamin D linked to increased relapse risk after HSCT for myeloid malignancies

Among patients with myeloid malignancies, vitamin D deficiency prior to undergoing allogeneic hematopoietic stem cell transplantation could affect disease control, find German researchers.

16-08-2017 | Rheumatology | News | Article

Decrease in walking speed predicts future OA risk

Results from an Osteoarthritis Initiative study suggest that people whose walking speed slows down over a 1-year period have an increased risk for developing knee osteoarthritis over the following 2 years compared with those who maintain a consistent pace.

Beyond the news

medwireNews@ESMO2016

medwireNews brings you news and conference reports from the ESMO 2016 Congress, held in Copenhagen, Denmark.

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medwireNews@EAN2015

Highlights from the 1st conference of the European Academy of Neurology in Berlin, Germany.

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