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Asthma

Eosinophilia linked to lung function decline irrespective of asthma symptoms

Blood sample

High blood eosinophil counts are associated with airflow obstruction and lung function decline in patients with asthma, but also in people without respiratory symptoms, population-based study findings show.

HBV

Updated AASLD guidance released on HBV prevention, diagnosis, and treatment

Folder_Binders in background

The American Association for the Study of Liver Diseases has issued a guidance statement for chronic hepatitis B virus, covering topics ranging from screening and prevention through to the clinical management of patients.

Oncology

Oxaliplatin HIPEC unnecessary for colorectal peritoneal carcinomatosis patients

HIPEC surgery

Oxaliplatin-based hyperthermic intraperitoneal chemotherapy after cytoreductive surgery does not improve the survival of colorectal cancer patients with peritoneal carcinomatosis, the PRODIGE 7 investigators report.

Rheumatology

Diclofenac linked to increased myocardial infarction risk in SpA patients

Heartbeat

Current use of the nonsteroidal anti-inflammatory drug diclofenac, but not of naproxen, is associated with a threefold increased risk for myocardial infarction among individuals with spondyloarthritis, according to recent findings.

Headlines from across medwireNews

17-06-2018 | Rheumatology | News | Article

Blood test predicts at-risk individuals likely to develop RA in the short term

Researchers have validated a blood test involving B-cell receptor clones that could determine which healthy individuals at risk for rheumatoid arthritis are likely to develop the condition in the short term.

16-06-2018 | Rheumatology | News | Article

Benefits of risankizumab maintained for 24 weeks in patients with PsA

Study results presented at the EULAR 2018 meeting in Amsterdam, the Netherlands, indicate that improvements in joint and skin symptoms seen with risankizumab treatment are maintained for 24 weeks among patients with psoriatic arthritis.

15-06-2018 | Rheumatology | News | Article

MRI monitoring of treated RA patients does not improve clinical and radiographic outcomes

Adding the additional target of no osteitis or bone marrow edema on magnetic resonance imaging to a conventional treat-to-target regimen does not improve the clinical or radiographic outcomes of rheumatoid arthritis patients in clinical remission, IMAGINE-RA study findings show.

15-06-2018 | Rheumatology | News | Article

Baricitinib shows promise in systemic lupus erythematosus

The addition of once-daily baricitinib to standard background therapy could improve clinical outcomes in patients with systemic lupus erythematosus, phase II trial findings show.

15-06-2018 | Rheumatology | News | Article

Self-harm risk increased following ankylosing spondylitis diagnosis

Researchers have found an increased risk for self-harm in patients with ankylosing spondylitis.

15-06-2018 | Non-small-cell lung cancer | News | Article

ARCHER 1050: Dacomitinib hits the OS target in advanced EGFR-mutated NSCLC

Patients with advanced non-small-cell cancer with activating EGFR mutations derive a significant overall survival benefit from first-line treatment with dacomitinib relative to gefitinib, the ARCHER 1050 trial shows.

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