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Response to canakinumab therapy is sustained or even improved for up to 5 years in children with systemic juvenile idiopathic arthritis, with no new safety signals, according to the results of a long-term extension study published in the Annals of the Rheumatic Diseases.

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A meta-analysis published in The BMJ suggests that diet only explains a small proportion of variation in serum uric acid levels, with genetic variation making a much larger contribution to hyperuricemia risk.

Results of a real-world study suggest that changing from a dry powder inhaler to a pressurized metered-dose inhaler is not associated with compromised treatment outcomes among patients with asthma.

Intralesional macular atrophy is common in individuals with neovascular age-related macular degeneration undergoing treatment with vascular endothelial growth factor inhibitors, study findings indicate.

Patients whose colon cancers are detected by routine screening have fewer postoperative complications than individuals whose cancers are diagnosed outside of a national programme, study findings indicate.