Histologic prostatitis linked to sexual dysfunction in BPH
medwireNews: Researchers from China say that urologists must be more alert to the presence of histologic prostatitis in patients with benign prostatic hyperplasia (BPH), after finding that it is significantly associated with the risk for sexual dysfunction.
Their study involved 160 patients who underwent plasma kinetic transurethral resection of the prostate during a 7-month period in 2012. The patients were divided into two groups of equal number: those with BPH and histologic prostatitis, and those with hyperplasia alone.
The team found that patients in the combined group had significantly worse erectile function on average than patients with hyperplasia alone, with a mean International Index for Erectile Function-5 score of 7.35 compared with 14.80.
Furthermore, no patient in the combined group was free from erectile dysfunction compared with 12 patients with hyperplasia alone. The rate of severe erectile dysfunction was 38 patients and 12 patients, respectively, while only 10 patients in the combined group had mild erectile dysfunction compared with 40 in the hyperplasia group.
These findings were despite similar characteristics between the two groups, including age (mean 72.0 and 72.6 years, respectively) and International Prostate Symptom Score (mean 20.50 and 18.65).
Bo Peng and colleagues, from Tongji University in Shanghai, say that several recent studies have pointed to histologic prostatitis as an important influence on the progression of BPH. They say their results now show that “prostatic hyperplasia plus histological prostatitis can bring about a large impact on a patient’s sexual function, suggesting that histological prostatitis is one of the major risk factors for sexual dysfunction.”
Writing in Urology, the authors add that the findings “may work as a reminder for urologists in the prevention and treatment of BPH, as well as sexual function disorders, emphasizing that sufficient attention should be paid to the development of prostatitis.”
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By Kirsty Oswald, medwireNews Reporter