Thyroid

A novel genomic sequencing classifier can identify cytologically indeterminate thyroid nodules that are benign with a high degree of sensitivity and accuracy, according to a blinded validation study.

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Preliminary findings for larotrectinib suggest that the agent may offer an effective tumor type-agnostic treatment for adults and children presenting with tropomyosin receptor kinase fusions.

A study of thyroid cancer prevalence after the Chernobyl disaster has shown that exposure to radioactive iodine increases the risk of thyroid cancer in children and adolescents.

UK scientists have found that individuals who have been treated for hyper- or hypothyroidism have no increased risk of mortality or serious vascular events, but they may have a greater risk for specific nonfatal vascular events.

Elderly patients should undergo thyroid function evaluation before and after contrast imaging because of the risk of iodine-induced hyperthyroidism through exposure to iodinated contrast media, clinicians say.

A study in rats has suggested that non-thyroidal illness syndrome, a generalized response to any serious illness, might be treatable by forced expression of steroid receptor co-activator.

A case report by Iranian scientists has detailed a multimodality treatment option that is effective for patients with follicular thyroid carcinoma who present with spinal cord compression.

Dietary iodine supplementation that is more than adequate or excessive does not appear to be safe, especially for susceptible populations who either have iodine deficiency or potential autoimmune thyroid diseases, researchers reporting in the

New England Journal of Medicine

say.

German scientists have found that there is a strikingly high spontaneous mutation rate in the thyroid gland.

US researchers have found that a high proportion of patients with sporadic primary hyperparathyroidism who have equivocal pre-operative imaging results can be cured with unilateral surgical exploration alone.

Japanese researchers have reported the case of a 28-year old woman with resistance to thyroid hormone and chronic thyroiditis.

Intraoperative measures of parathyroid hormone level show high accuracy in the prediction of outcomes from parathyroid surgery for primary hyperparathyroidism, Swedish scientists have shown.

Clinicians may be able to distinguish between parathyroid adenomas and parathyroid proliferative lesions by virtue of increased angiogenesis in the former, Greek scientists believe.

Study findings show that eating a low calorie, yet nutritionally balanced diet lowers concentrations of triiodothyronine.

Scientists have discovered that thyroidectomy can be performed using a new surgical method that involves an incision about half the length used for traditional surgery, combined with ultrasonic technology.

Celecoxib does not halt the development of progressive metastatic differentiated thyroid cancer in most patients, US scientists have found.

Researchers advise that preoperative screening with ultrasonography should be a standard part of the initial operative treatment for papillary thyroid cancer.

Italian investigators have confirmed that there is a strong link between thyroid autoimmunity and breast cancer, and that this link is independent of the effects of mastectomy-induced stress.