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Thrombosis

Thrombosis

06-01-2017 | Thrombosis | News | Article

Targeting PAR4 ‘an attractive antiplatelet strategy’

Results of a study conducted in primates suggest that a novel protease-activated receptor-4 antagonist could reduce thrombus formation with a lower bleeding risk than other antiplatelet agents.

15-12-2016 | Acute coronary syndromes | News | Article

Antithrombotic treatment before coronary angiography associated with excess bleeding

Treatment with antithrombotic drugs before coronary angiography is associated with excess bleeding in patients with non–ST-segment elevation acute coronary syndromes, study results suggest.

06-12-2016 | Thrombosis | News | Article

Oral thrombin inhibitor treatment could increase blood clot formation

The oral thrombin inhibitor dabigatran may actually increase thrombus formation, suggest the results of a translational study conducted in human arterial plaque and mouse models of blood clotting.

31-08-2016 | Cardiology | News | Article

Adanexanet substantially reduces anti-FXa in bleeding patients

Adanexanet rapidly reverses anti-factor Xa activity in patients with acute major bleeding associated with FXa inhibitors, preliminary results from the ANNEXA-4 study show.

31-05-2016 | Thrombosis | News | Article

Betrixaban scores near miss for extended thromboprophylaxis

Extended thromboprophylaxis with the direct factor Xa inhibitor betrixaban just fails to show superiority to standard treatment with enoxaparin in acutely ill medical patients.

04-09-2013 | Cardiology | Article

Asthma exacerbates PE risk

Data from Taiwan show that asthma is associated with a significant increase in the risk for pulmonary embolism, particularly in patients who experience exacerbations.

29-07-2013 | Cardiology | Article

PE presents ‘therapeutic challenge’ in COPD

Researchers have found that those patients who develop pulmonary embolism have the poorest outcomes among chronic obstructive pulmonary disease patients with venous thromboembolism.

20-05-2013 | Cardiology | Article

Rheumatoid arthritis linked to VTE risk

Patients with rheumatoid arthritis have a significantly elevated risk for venous thromboembolism, suggest study findings published in Arthritis Care and Research.

24-02-2013 | Cardiology | Article

Protamine–heparin complex antibodies raise concerns

Almost a third of patients treated with protamine for heparin reversal during cardiopulmonary bypass develop antibodies to circulating protamine–heparin complexes, study findings suggest.

24-02-2013 | Cardiology | Article

WOEST supports clopidogrel only in PCI patients on anticoagulation

Publication of the WOEST trial results reaffirm the study’s major finding that antiplatelet therapy with clopidogrel alone is preferable to the use of both aspirin and clopidogrel in patients undergoing percutaneous coronary intervention who are receiving oral anticoagulant therapy.

19-02-2013 | Cardiology | Article

Blood type, blood protein mutations influence thromboembolism risk

Findings from two Danish studies have shown that ABO blood type, both alone and in combination with the presence of factor V and prothrombin mutations, is associated with increases in risk for venous thromboembolism.

12-02-2013 | Cardiology | Article

Rivaroxaban ruled out for extended thromboprophylaxis

The benefits of extended prophylactic anticoagulation with rivaroxaban in acutely ill hospital patients are outweighed by an increased bleeding risk, shows a study in The New England Journal of Medicine.

16-01-2013 | Cardiology | Article

Hypercoagulable markers identified in upper arm thrombosis patients

Coagulation tests are warranted in young women undergoing surgery for subclavian vein thrombosis, especially patients with Paget-Schroetter syndrome unrelated to physical activity, say US clinicians.

01-01-2013 | Cardiology | Article

Thromboprophylaxis does more harm than good in head and neck surgery

Patients undergoing oncologic head and neck surgery do not benefit from thromboprophylaxis, report researchers.

30-12-2012 | Cardiology | Article

Stent placement ‘effective alternative to IVT in stroke patients’

In stroke patients in whom intravenous thrombolysis is either contraindicated or has failed, intra-arterial revascularization with cerebral angioplasty and stent placement is an effective and well-tolerated treatment, say Czech researchers.

20-11-2012 | Cardiology | Article

Cryoprecipitate plus tranexamic acid boost war injury survival

Administration of cryoprecipitate and tranexamic acid significantly improves the likelihood of survival among seriously injured patients requiring packed red blood cells, suggest results from MATTERS II.

17-10-2012 | Cardiology | Article

Reduced copayment policy has benefits all round

Reducing patients’ copayments for statins and clopidogrel could increase their adherence without adding financial burden to the healthcare system, researchers say.

09-10-2012 | Cardiology | Article

Hemophilia bleeding risk ‘low’ for childhood sports

Vigorous physical activity is associated with a moderate but transient bleeding risk for hemophilia, resulting in an overall low risk for bleeds, suggests a study of Australian children.

07-10-2012 | Cardiology | Article

VTE risk highlighted for rheumatoid arthritis patients

Individuals with rheumatoid arthritis are at an increased risk for venous thromboembolism, research confirms.

02-10-2012 | Cardiology | Article

Stent fracture after stent implantation linked to thrombosis

Stent fracture after everolimus-eluting stent implantation occurs in 2.9% of lesions and is associated with a significantly increased rate of major adverse cardiac events, say researchers.

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