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Differential DNA methylation may help identify likely methotrexate responders


Changes in DNA methylation following initiation of methotrexate appear to correlate with response to the drug in patients with rheumatoid arthritis, study findings indicate.

Elevated IFN-α linked to relapse risk in SLE

Blood sample

A quarter of patients in remission for systemic lupus erythematosus have elevated serum interferon-α levels and may be at increased risk for relapse, French researchers report.

Continuous NSAID use linked to hypertension risk in ankylosing spondylitis

blood pressure measurement

Individuals with ankylosing spondylitis who continually use NSAIDs have an increased risk for hypertension relative to those who use the drugs less frequently, study findings indicate.

17-10-2019 | Rheumatology | News | Article

Treatment switching associated with VTE risk in RA

People with rheumatoid arthritis who switch between different biologic or targeted synthetic DMARDs have a higher risk for venous thromboembolism than those who remain on the same treatment, researchers report.

15-10-2019 | Rheumatology | News | Article

FDA approves rituximab for rare pediatric vasculitides

Click through for more details on this approval

14-10-2019 | Rheumatology | News | Article

IBS an ‘overlooked’ comorbidity in axSpA patients

Around a third of individuals with axial spondyloarthritis exhibit gut-related symptoms characteristic of irritable bowel syndrome, finds an analysis of a population-based study.

11-10-2019 | Rheumatology | News | Article

Lympho-myeloid pathotype linked to more aggressive disease in RA

Having a lympho-myeloid pathotype at onset of rheumatoid arthritis is associated with an increased subsequent need for biologic therapy, irrespective of clinical classification, study findings indicate.

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