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Rheumatology

NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

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People with osteoarthritis have a significantly higher risk for developing cardiovascular disease than those without, and the use of nonsteroidal anti-inflammatory drugs mediates a considerable proportion of this association, researchers report.

Machine learning shows promise for predicting TNF inhibitor response

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A machine-learning model may help to predict which rheumatoid arthritis patients are likely to respond to treatment with TNF inhibitors, researchers report.

FINCH 2: Further evidence for filgotinib as a treatment option for RA

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Rheumatoid arthritis (RA) patients with an inadequate response or intolerance to biologic DMARDs who are treated with the selective JAK1 inhibitor filgotinib are more likely to achieve a clinical response than those given placebo, phase III trial results suggest.

16-08-2019 | Rheumatology | News | Article

Frailty linked to worsening function in RA patients

Frailty may be a risk factor for worsening physical function among people with rheumatoid arthritis, research suggests.

15-08-2019 | Rheumatology | News | Article

Preoperative opioid use linked to adverse outcomes after knee replacement

Among people with osteoarthritis or rheumatoid arthritis who undergo total knee replacement, continuous preoperative opioid use is associated with an increased risk for adverse outcomes, study findings suggest.

14-08-2019 | Rheumatology | News | Article

Support for switching between upadacitinib and adalimumab in RA patients

48-week results from the SELECT-COMPARE study indicate that upadacitinib has sustained efficacy in patients with rheumatoid arthritis, and that individuals with an inadequate response to upadacitinib or adalimumab may benefit from switching to the alternate therapy.

14-08-2019 | Rheumatology | News | Article

Vaccination may increase gout flare risk

The increased risk for gout flares following receipt of the aluminum-free recombinant zoster vaccine is not unique to this vaccine but is instead associated with vaccination in general, regardless of the adjuvant used, US researchers report.

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