Expanded indication for anakinra recommended by EMA
medwireNews: The EMA has recommended expanding the indication of anakinra to include systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD).
The interleukin-1 receptor inhibitor is currently approved for the treatment of rheumatoid arthritis in combination with methotrexate for patients with an inadequate response to methotrexate alone, as well as for cryopyrin-associated periodic syndromes.
It is recommended that anakinra may now be given to sJIA or AOSD patients with moderate-to-high disease activity, or those with an inadequate response to treatment with nonsteroidal anti-inflammatory drugs or glucocorticoids.
The EMA states that anakinra can be given as monotherapy or together with other anti-inflammatory drugs or DMARDs.
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