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Rheumatology

Rheumatology

21-09-2021 | Rheumatology | News | Article

Osteoarthritis prevalent and onset accelerated in women with PCOS

Women with polycystic ovary syndrome have a higher prevalence and accelerated onset of osteoarthritis in both weight and non-weight bearing joints than the general population, according to an analysis of data from two Danish-based registries.

20-09-2021 | Rheumatology | News | Article

Recurrent RA joint swelling tends to affect same joints each time

Localized inflammatory factors may play a role in joint swelling among people with rheumatoid arthritis, say researchers who found that swelling tends to recur in the same joints over time.

17-09-2021 | Rheumatology | News | Article

Smoking, BMI mediate impact of education on RA

Higher educational attainment, as a marker of socioeconomic position, is associated with a lower risk for rheumatoid arthritis, but this protective effect can be moderated by smoking and BMI, suggests an analysis of genetic data.

16-09-2021 | Rheumatology | News | Article

Low rates of breakthrough SARS-CoV-2 infection after vaccination in people with RMDs

Preliminary findings from two studies point to low overall rates of breakthrough COVID-19 following vaccination in people with rheumatic and musculoskeletal diseases.

16-09-2021 | Rheumatology | News | Article

Booster dose may enhance COVID-19 vaccination response in people with autoimmune disease

Having a booster dose of vaccine against SARS-CoV-2 augments the humoral immune response in the majority of people with immune-mediated inflammatory diseases, suggest findings from a small study.

15-09-2021 | Rheumatology | News | Article

EULAR releases guidance on managing difficult-to-treat RA

EULAR has issued evidence-based points to consider for the management of difficult-to-treat rheumatoid arthritis.

14-09-2021 | Rheumatology | News | Article

Mediterranean diet may be beneficial for people with axSpA

Improved adherence to a Mediterranean dietary pattern is associated with a reduction in disease activity among people with axial spondyloarthritis, indicate findings from an Italian observational study.

13-09-2021 | Rheumatology | News | Article

Better immune response with mRNA vs adenovirus-based COVID-19 vaccines in RMD patients

Preliminary results from a US study suggest that mRNA vaccines against COVID-19 may elicit a stronger immune response than adenovirus-based vaccines among people with rheumatic and musculoskeletal diseases.

13-09-2021 | Rheumatology | News | Article

Study identifies predictors of COVID-19 vaccine response in rituximab-treated patients

Among people treated with anti-CD20 B cell-depleting agents, timing of treatment and numbers of circulating CD4+ and CD19+ cells are significant predictors of immune responses to messenger (m)RNA vaccines against SARS-CoV-2, shows the RituxiVac study.

10-09-2021 | Rheumatology | News | Article

Novel frailty index predicts adverse health outcomes in longstanding SLE

An external validation study suggests that the novel Systemic Lupus International Collaborating Clinics frailty index predicts organ damage accrual and mortality risk in patients with longstanding systemic lupus erythematosus.

09-09-2021 | Rheumatology | News | Article

Favorable outcomes in pregnant women with RMDs and COVID-19

Preliminary study results from the COVID-19 Global Rheumatology Alliance suggest that pregnant women with rheumatic and musculoskeletal diseases have generally favorable outcomes following SARS-CoV-2 infection.

08-09-2021 | Rheumatology | News | Article

Meta-analysis bolsters link between rheumatic and cardiovascular disease

Both systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for symptomatic cardiovascular events but data are lacking for asymptomatic events, results of a systematic review and meta-analysis show.

07-09-2021 | Rheumatology | News | Article

COVID-19 vaccination: Meta-analysis confirms reduced seroconversion rates in people with IMIDs

People with immune-mediated inflammatory diseases, particularly those on rituximab or abatacept, may have a reduced antibody response to mRNA SARS-CoV-2 vaccines relative to the general population, show findings from a systematic review and meta-analysis.

06-09-2021 | Rheumatology | News | Article

Glucocorticoids, B-cell depleting therapies may dampen immune response to COVID-19 vaccines

Most people with inflammatory diseases treated with immunomodulatory therapies mount an antibody response to mRNA vaccines against SARS-CoV-2, but the response may be blunted in those taking glucocorticoids or B cell-depleting therapies, shows the COVaRiPAD study.

03-09-2021 | Rheumatology | News | Article

Anakinra may benefit people with moderate-to-severe COVID-19

Treatment with the IL-1 receptor antagonist anakinra may reduce mortality risk versus standard care in people with moderate-to-severe COVID-19, particularly those with hyperinflammation, suggests a systematic review and patient-level meta-analysis.

02-09-2021 | Rheumatology | News | Article

FDA requires boxed warning updates for JAK inhibitors

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02-09-2021 | Rheumatology | News | Article

Meta-analysis underscores risk for adverse pregnancy outcomes in women with SpA

Findings from a systematic review and meta-analysis suggest that spondyloarthritis is associated with an elevated risk for adverse pregnancy outcomes, including preterm birth and preeclampsia.

01-09-2021 | Rheumatology | News | Article

ELAG: Similar gout flare outcomes with early vs late allopurinol initiation

Early initiation of allopurinol during an acute gout flare does not impact time to resolution or rates of recurrent flare, suggest findings from a randomized controlled trial.

31-08-2021 | Rheumatology | News | Article

Early-onset primary Sjögren’s syndrome linked to more severe disease

People who develop early-onset primary Sjögren’s syndrome have “strikingly more severe disease activity” and greater activation of the cellular immune system compared with those diagnosed at a later age, researchers report.

27-08-2021 | Rheumatology | News | Article

Increased rates of JIA flare during COVID-19 lockdown

Children with juvenile idiopathic arthritis experienced increased rates of flare during the COVID-19 lockdown period, suggest findings from an Italian cohort study.

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