Classifying individuals with musculoskeletal symptoms and no clinical synovitis using anti-cyclic citrullinated peptide antibody levels and self-reported hand or foot pain may be useful to prioritize rheumatology referrals, study findings indicate.
Interstitial lung disease affects a substantial proportion of patients with rheumatoid arthritis and is associated with reduced survival, but the condition is overlooked by clinicians, suggest results from a population-based study.
A third dose of the Pfizer–BioNTech vaccine gives rise to a neutralizing antibody response in the majority of people with ANCA-associated vasculitis, but those treated with rituximab are unlikely to respond, researchers report.
It is possible for rituximab-treated patients with no response to two mRNA vaccines against SARS-CoV-2 to respond to a third dose, with similar response rates among those switching to a vector vaccine and those given a third dose of the same vaccine, research suggests.
People with psoriatic arthritis have an increased risk for venous thromboembolism relative to the general population, and this association is likely to be related to underlying comorbidities, research suggests.
Cumulative prednisone dose and effective disease control are both associated with increased BMI among patients with giant cell arteritis, post-hoc analysis of the GiACTA trial suggests.
Treatment with any of the five JAK inhibitors approved for use in rheumatoid arthritis in the USA, Europe, or Japan may lead to an increase in serum cholesterol levels, suggest results of a systematic review and network meta-analysis.
Adding duloxetine to usual care does not improve pain outcomes for people with chronic osteoarthritis, suggest findings from a randomized controlled trial conducted in the primary care setting.
Researchers have identified a minimum level of B cells in the peripheral circulation that may serve as a biomarker for response to COVID-19 vaccines among rituximab-treated patients.
Findings from two studies suggest that among rituximab-treated patients, those with a longer time since their last infusion may be more likely to have an antibody response to vaccines against SARS-CoV-2.
African–American women with systemic lupus erythematosus have an increased risk for delivering preterm or small for gestational age infants, even in the years immediately before their diagnosis, US study findings indicate.
Expression of the proinflammatory cytokine interleukin-16 strongly correlates with histologic activity in people undergoing treatment for lupus nephritis, shows a longitudinal study of urinary proteomic profiles.