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Pulmonary arterial hypertension

Pulmonary arterial hypertension

04-07-2016 | Pulmonary hypertension | News | Article

Circulating angiogenic factor shows PAH biomarker potential

Hepatoma-derived growth factor predicts disease severity and survival in patients with pulmonary arterial hypertension, showing some possible clinical advantages over N-terminal pro-brain natriuretic peptide, researchers report.

15-06-2016 | Pulmonary hypertension | News | Article

Potential non-invasive screening biomarker for SSc-PAH

Serum asymmetric dimethylarginine may be an effective non-invasive screening biomarker for systemic sclerosis-related pulmonary arterial hypertension, study findings indicate.

14-06-2016 | Pulmonary hypertension | News | Article

Right ventricular echocardiography predicts targeted therapy outcome in PAH

Echocardiography re-assessment of right ventricular function after targeted therapy is sufficient to predict subsequent prognosis in patients with pulmonary arterial hypertension, say researchers.

08-06-2016 | Pulmonary hypertension | News | Article

Reduced RV functional reserve may explain poor SSc-PAH outcomes

Patients who develop pulmonary arterial hypertension as a consequence of systemic sclerosis have poorer right ventricular functional reserve than those with idiopathic disease, research published in Circulation shows.

06-05-2016 | Pulmonary hypertension | News | Article

Elevated endothelial progenitor cells may characterise PAH patients

Plasma levels of endothelial progenitor cells are elevated in patients with pulmonary arterial hypertension, say researchers.

05-05-2016 | Pulmonary hypertension | News | Article

Pulmonary hypertension impacts walking ability in SSc patients

The results of a meta-analysis show the adverse impact pulmonary hypertension has on the walking stamina of patients with systemic sclerosis.

05-05-2016 | Pulmonary hypertension | News | Article

More evidence for combination therapy benefits in PAH

Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy.

25-04-2016 | Pulmonary hypertension | News | Article

Meta-analysis supports combination therapy for PAH patients

A meta-analysis shows that clinical worsening is significantly less likely in patients with pulmonary arterial hypertension if they are given combination treatment, rather than monotherapy.

13-04-2016 | Pulmonary hypertension | News | Article

Minimally important dyspnoea, fatigue changes in PAH patients defined

Researchers say that a change of around 1 unit in Borg dyspnoea or fatigue scores signifies an important change in patients with pulmonary arterial hypertension.

12-04-2016 | Pulmonary hypertension | News | Article

Increased BMP7 levels predict PAH mortality

Elevated levels of circulating bone morphogenetic protein 7 are associated with an increased mortality risk in patients with pulmonary arterial hypertension, find Chinese researchers.

09-03-2016 | Pulmonary hypertension | News | Article

Tricuspid regurgitation tied to outcomes in PAH patients

Tricuspid regurgitation progresses in line with right ventricular remodelling and increasing pulmonary artery systolic pressure in patients with pulmonary arterial hypertension, research shows.

09-03-2016 | Pulmonary hypertension | News | Article

Regulatory immune cells compromised in PAH

Research suggests that regulatory T cells may play a part in all subtypes of pulmonary arterial hypertension.

09-03-2016 | Pulmonary hypertension | News | Article

PAH role proposed for left heart failure biomarker

Levels of galectin-3 are elevated in patients with pulmonary arterial hypertension and correlate with disease severity, research shows.

09-02-2016 | Pulmonary hypertension | News | Article

Left ventricular tissue phase mapping predicts PAH outcomes

A tissue phase mapping study shows that left ventricular function is abnormal in patients with pulmonary arterial hypertension and is linked to clinical outcomes.

05-02-2016 | Pulmonary hypertension | News | Article

Ambrisentan avoids sildenafil drug interaction in PAH patients

Sildenafil may be better given to pulmonary arterial hypertension patients in combination with ambrisentan than with bosentan, study findings suggest.

03-02-2016 | Pulmonary hypertension | News | Article

BMPR2 gene mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

08-01-2016 | Pulmonary hypertension | News | Article

PAH rare in systemic lupus erythematosus

The prevalence of pulmonary arterial hypertension is very low among patients with systemic lupus erythematosus, say researchers.

08-01-2016 | Pulmonary hypertension | News | Article

Weight of evidence supports exercise training in PAH

Exercise training is a “promising intervention”, alongside medical treatment, in patients with pulmonary arterial hypertension (PAH), say the authors of a systematic review.

07-01-2016 | Pulmonary hypertension | News | Article

Selexipag reduces clinical events in PAH patients

Selexipag, alone or in combination with other classes of pulmonary arterial hypertension medication, reduced the composite rate of disease complications and deaths among patients in a phase III trial.

07-01-2016 | Pulmonary hypertension | News | Article

Arrhythmias worth treating in PAH patients

Supraventricular arrhythmias are common in patients with pulmonary arterial hypertension but can be successfully managed with standard treatments, a study shows.