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Parkinson's disease

Parkinson's disease

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13-01-2016 | Parkinson's disease | News | Article

Anticholinesterase offers a ‘steadying hand’ to PD patients

The dementia drug rivastigmine may reduce the risk of falls in patients with Parkinson’s disease by improving gait stability, findings from the phase II ReSponD trial show.

12-01-2016 | Parkinson's disease | News | Article

Weight loss may mark rapid Parkinson’s disease progression

Weight loss in patients with early Parkinson’s disease is associated with worsening motor function, research shows.

23-12-2015 | Parkinson's disease | News | Article

Opicapone simplifies levodopa-related motor fluctuation treatment

Once-daily opicapone is effective for the treatment of end-of-dose motor fluctuations in patients receiving levodopa for Parkinson’s disease, phase III study findings show.

21-12-2015 | Movement disorders | News | Article

‘Gunslinger’s gait’ should be included in differential diagnosis

An analysis of the gait of top Russian officials has led researchers to warn neurologists against interpreting a probable behavioural adaptation as a pathological gait pattern.

26-11-2015 | Parkinson's disease | News | Article

Rare variants linked with Parkinson’s disease

Researchers using exome sequencing in families with Parkinson’s disease have identified two genes that could be associated with the condition.

21-10-2015 | Parkinson's disease | News | Article

Support for enteric nervous system pathology in prodromal PD

Researchers have found positive immunostaining of α-synuclein in the enteric nervous system of patients with idiopathic rapid eye movement sleep behaviour disorder, suggesting it may have a possible role as a biomarker for prodromal Parkinson’s disease.

09-10-2015 | Parkinson's disease | News | Article

Cognitive decline common and rapid in Parkinson’s patients

Researchers report that nearly half of patients with Parkinson’s disease develop cognitive impairment within about a decade, and progress rapidly to dementia.

08-10-2015 | Parkinson's disease | News | Article

Minor hallucinations may predate Parkinson motor symptoms

About four in 10 patients with untreated Parkinson’s disease experience minor hallucinations, research shows.

18-09-2015 | Parkinson's disease | News | Article

Olfactory function may inform Parkinson’s prognosis

Olfactory function is preserved in about a quarter of patients with Parkinson’s disease, and may be predictive of disease course, say researchers.

03-09-2015 | Parkinson's disease | News | Article

Cognitive impairment may be part of prodromal PD

Research shows that people with a theoretical high risk of developing Parkinson’s disease have significant cognitive deficits, particularly affecting executive function.

19-08-2015 | Parkinson's disease | News | Article

CSF biomarkers predict dementia risk in PD patients

Early analysis of cerebrospinal fluid could help diagnose parkinsonian disorders and enhance the prediction of dementia in Parkinson’s disease patients, study results indicate.

17-08-2015 | Parkinson's disease | News | Article

Putaminal serotonergic innervation flags levodopa-induced dyskinesia risk

Increased serotonergic fibre innervation relative to dopaminergic fibre availability may be a potential marker of disease progression in Parkinson’s disease patients and a possible warning of levodopa-induced dyskinesia, indicates an in vivo imaging study.

13-08-2015 | Parkinson's disease | News | Article

Algorithm encompassing clinical and genetic factors predicts PD

Researchers have devised a model that distinguishes patients with Parkinson’s disease from those without the condition without relying on motor features.

05-08-2015 | Parkinson's disease | News | Article

Early cognitive changes linked to white matter damage in Parkinson’s

Subtle changes in white matter integrity are detectable in patients with Parkinson’s disease and are associated with early impairments in cognition, say researchers.

04-08-2015 | Parkinson's disease | News | Article

Neurologists have key end-of-life role for Parkinson’s patients

Around a quarter of patients with Parkinson’s disease end up in a long-term care facility or nursing home, say researchers who highlight the role of neurologists in improving these patients’ care.

03-08-2015 | Parkinson's disease | News | Article

DBS may aid cortical plasticity in Parkinson’s patients

Deep-brain stimulation of the subthalamic nucleus may help to restore long-term potentiation-like plasticity in the motor cortex of patients with Parkinson’s disease, a study shows.

09-07-2015 | Parkinson's disease | News | Article

Severe dyskinesias rare in community Parkinson’s cohort

Motor fluctuations and dyskinesias affect about a third of community-based patients with Parkinson’s disease, but dyskinesias are rarely severe enough to warrant a change of treatment, report researchers.

03-07-2015 | Parkinson's disease | News | Article

Increased sleepiness may necessitate cautious PD management

Many patients with early Parkinson’s disease develop excessive daytime sleepiness as their condition progresses, a study shows.

Elderly woman_pills

22-06-2015 | Parkinson's disease | News | Article

Opioid offers pain relief for Parkinson’s patients

Prolonged-release combined oxycodone/naloxone may provide relief for patients with severe pain related to Parkinson’s disease, a double-blind randomised trial shows.

19-06-2015 | Parkinson's disease | News | Article

PD linked to increased cancer risk in Asian population

A Taiwanese population-based cohort study reports an increased risk of most cancers in patients with Parkinson’s disease, contrasting with findings in Western populations.