Pediatrics

The risk of relapse after treatment for childhood acute lymphoblastic leukaemia has decreased in the past 3 decades but the likelihood of successful treatment of relapse has not improved, suggests a review of three Nordic Society of Pediatric Hematology and Oncology clinical trials.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Children diagnosed with attention deficit/hyperactivity disorder before puberty have evidence of changes in their gut microbiota before the age of 1 year, research shows.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Children and adolescents using an advanced hybrid closed-loop system for type 1 diabetes can tolerate an unannounced snack containing 20 g of carbohydrate without excessive blood sugar fluctuations, Italian researchers report.

Screening for mitogen-activated protein kinase signalling pathway alterations in children and young adults with cancer or histiocytic disorders is feasible, but targeted therapy with selumetinib showed “limited efficacy” in this population, say the NCI-COG Pediatric MATCH trial investigators.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.