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Paediatrics

Paediatrics

28-09-2020 | Diabetes | News | Article

C-peptide a reliable guide to residual beta cells across ages, diabetes durations

Levels of circulating C-peptide in people with type 1 diabetes reflect the numbers of remaining beta cells across different ages at diagnosis and durations of disease, confirm UK researchers.

26-08-2020 | Diabetes | News | Article

​​​​​​​Closed-loop system improves glycemic control in children with type 1 diabetes

Children with type 1 diabetes who use the Tandem Control-IQ hybrid closed-loop insulin delivery system spend more time with their blood glucose levels in the target range than those using a sensor-augmented insulin pump, show findings from the iDCL trial.

25-08-2020 | Rheumatology | News | Article

Canakinumab monotherapy tapering feasible in systemic JIA

Canakinumab monotherapy tapering, either through dose reduction or dose interval prolongation, is feasible in children with systemic juvenile idiopathic arthritis who achieve clinical remission, study findings indicate.

26-05-2020 | Multiple sclerosis | Video

EAN 2020 | Teriflunomide shows benefits in children with relapsing forms of MS

Tanuja Chitnis tells us about the TERIKIDS study showing a numerical reduction in clinical relapse risk and a significant reduction in time to clinical relapse with teriflunomide  in paediatric patients with relapsing-remitting multiple sclerosis (5:29).

08-01-2020 | Diabetes | News | Article

Early puberty may raise type 2 diabetes risk in women

Earlier age at menarche is associated with an increased risk for type 2 diabetes and impaired glucose tolerance among women, and this association remains significant after adjustment for adiposity, suggest findings from a meta-analysis.

30-08-2019 | Rheumatology | News | Article

Observational data support long-term adalimumab use in polyarticular JIA

Adalimumab, used with or without concurrent methotrexate, appears to be well tolerated among children with polyarticular‐course juvenile idiopathic arthritis, 7-year data from the STRIVE registry show.

08-08-2019 | Diabetes | News | Article

Pros and cons of CGM described by parents of children with diabetes

Continuous glucose monitoring offers many benefits to the families of young children with type 1 diabetes but also a number of challenges that cannot always be overcome, show results of a qualitative analysis conducted in the USA.

09-05-2019 | Multiple sclerosis | Video

AAN 2019: Paediatric MS disability scoring system developed

Jonathan Santoro summarises their research evaluating disability distribution in paediatric-onset multiple sclerosis using a novel scoring model, and discusses the implications for the care of patients (4:31).

26-04-2019 | Diabetes | News | Article

School-based consultations boost diabetes clinic attendance in hard-to-reach teens

Meeting teenagers with diabetes at their schools to discuss concerns and reflect on self-management reduces the number who do not attend hospital clinics, say researchers.

04-04-2019 | Oncology | News | Article

LOXO-195 could be an option for tumors resistant to first-generation TRK inhibitors

Early findings point to the antitumor efficacy of the next-generation TRK inhibitor LOXO-195 in patients with NTRK fusion-positive cancers and NTRK resistance mutations acquired during treatment with first-generation agents.

04-01-2019 | Oncology | News | Article

Atezolizumab, larotrectinib approvals announced by FDA

More information on use of these agents here

Preschool weight gain confers highest risk for teenage obesity

Endocrine Society updates 21-hydroxylase deficiency CAH guidelines

Latest GeNeSIS data confirm rhGH efficacy and long-term safety profile

Complications common in phenotypically normal male 45,X/46,XY patients

12-09-2018 | Leukaemia | News | Article

Levofloxacin reduces bacteremia during chemotherapy for childhood leukemia

Levofloxacin prophylaxis significantly reduces the risk for bacteremia among children receiving intensive chemotherapy for acute leukemia, but not among those undergoing hematopoietic stem cell transplantation, study data show.

11-09-2018 | Leukaemia | News | Article

Maternal hormonal contraceptive use linked to childhood non-lymphoid leukemia risk

The use of hormonal contraceptives just before and during pregnancy may significantly increase the risk for childhood non-lymphoid leukemia, Danish researchers report.

Mental, motor benefits accrue in Prader–Willi syndrome over longer-term GH treatment

Ethnicity influences reversibility of dysglycaemia in obese children

Concerns of Silver–Russell syndrome patients extend beyond height

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