Paediatrics

Researchers identify novel loci that may contribute to the success of asthma treatment in children of African descent, but find these differ between adolescents and younger children.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Altering and reintroducing the haematopoietic stem and progenitor cells of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma, with age and tumour stage possible risk factors for this diagnosis.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

The bile acid transport inhibitor maralixibat, given at a higher dose than previously tested, may significantly improve cholestasis in children with Alagille syndrome, shows the phase 2 ICONIC trial.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Intranasal oxytocin therapy did not improve the social or cognitive functioning of children and adolescents with autism in a randomised trial published in The New England Journal of Medicine.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Hybrid closed-loop therapy significantly improves glycemic control and quality of life relative to continuous subcutaneous insulin infusion or multiple daily insulin injections in children and adolescents with type 1 diabetes, research shows.

The risk of high-frequency hearing loss in children undergoing cancer treatment to the central nervous system or the head and neck could be reduced by minimising doses of radiation to the cochlea and limiting cumulative doses of cisplatin or carboplatin, Canadian researchers say.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

Impaired hypoglycemia awareness is present in a substantial proportion of children and young people with type 1 diabetes and is associated with an increased risk for severe hypoglycemia, suggests research presented at the virtual 57th EASD Annual Meeting.

Using a linear insulin to carbohydrate ratio to determine breakfast insulin requirements leads to significant differences in time in glycemic range and hypoglycemia rates when meal carbohydrate quantities vary, shows a study in children and young adults.