Skip to main content
main-content

Paediatrics

Paediatrics

23-06-2022 | Oncology | News | Article

Nordic childhood ALL review shows ‘fewer’ but ‘harder-to-cure’ relapses

The risk of relapse after treatment for childhood acute lymphoblastic leukaemia has decreased in the past 3 decades but the likelihood of successful treatment of relapse has not improved, suggests a review of three Nordic Society of Pediatric Hematology and Oncology clinical trials.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

14-06-2022 | Paediatrics | News | Article

Gut microbiota changes in infancy herald childhood ADHD diagnosis

Children diagnosed with attention deficit/hyperactivity disorder before puberty have evidence of changes in their gut microbiota before the age of 1 year, research shows.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

13-06-2022 | Diabetes | News | Article

Researchers calculate unannounced snack threshold for closed-loop system

Children and adolescents using an advanced hybrid closed-loop system for type 1 diabetes can tolerate an unannounced snack containing 20 g of carbohydrate without excessive blood sugar fluctuations, Italian researchers report.

02-06-2022 | Oncology | News | Article

Selumetinib shows ‘limited efficacy’ for paediatric tumours with MAPK pathway alterations

Screening for mitogen-activated protein kinase signalling pathway alterations in children and young adults with cancer or histiocytic disorders is feasible, but targeted therapy with selumetinib showed “limited efficacy” in this population, say the NCI-COG Pediatric MATCH trial investigators.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

No influence of age on burosumab response in X-linked hypophosphatemia

Logistic issues hinder transition from paediatric to adult endocrine care

rhGH therapy boosts adult height among children with SHOX haploinsufficiency

21-04-2022 | Oncology | News | Article

Childhood cancer AEs may be under-reported by clinicians

Children undergoing treatment for cancer report significantly more symptomatic adverse events than their clinicians but fewer than their caregivers, suggests research comparing assessments for triads of patients, caregivers and clinicians.

20-04-2022 | Diabetes | News | Article

Machine-learning tool could aid earlier diagnosis of type 1 diabetes

Researchers have developed a machine-learning tool that could predict a type 1 diabetes diagnosis in children on the basis of data from primary care electronic health records.

14-04-2022 | Rheumatology | News | Article

IL-1Ra autoantibodies may contribute to MIS-C pathophysiology

Autoantibodies against IL-1Ra are present in a large proportion of patients with MIS-C, say researchers.

Silver-Russell syndrome patients derive lasting height and BMI benefits from rhGH treatment

Growth hormone benefit in Noonan syndrome demonstrated regardless of PTPN11 mutation status

Switch from daily to weekly rhGH feasible and popular for children with GHD

31-03-2022 | Oncology | News | Article

‘Reassuring’ findings for COVID-19 risks among childhood cancer survivors

Child, adolescent and young adult survivors of childhood cancer do not have a greater risk of COVID-19 infection and severe illness than individuals without a history of cancer, suggest findings from a population-based study published in the Journal of Clinical Oncology.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

24-03-2022 | Rheumatology | News | Article

Network meta-analysis rates treatments for Kawasaki disease

Adding infliximab to standard therapy with high-dose intravenous immunoglobulin plus high-dose aspirin may decrease fever duration and prevent coronary artery lesions in children with Kawasaki disease, study findings indicate.

24-03-2022 | Paediatrics | News | Article

Early promise for adeno-associated virus gene therapy in Tay–Sachs disease

Replacement of the enzymes lacking in Tay–Sachs disease using adeno-associated virus gene therapy via both the thalamus and cerebrospinal fluid is possible and potentially efficacious in humans, shows a study in Nature Medicine.

This independent news story was supported by an educational grant from L’Institut Servier, Suresnes, France.

17-03-2022 | Rheumatology | News | Article

ACR–Vasculitis Foundation guidelines for Kawasaki disease published

Click through for more information

15-03-2022 | Rheumatology | News | Article

ACR issues two updated guidelines for JIA treatment

Click through for additional details

11-03-2022 | Diabetes | News | Article

Insulin pump infusion set failures most common in youngest users

Insulin pump infusion set failures that result in prolonged hyperglycemia occur an average of four times per year per user and are more common in children and adolescents than adults, US study findings indicate.

Early-life growth linked to pubertal timing