Other current therapy areas

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

Long-term tenofovir disoproxil fumarate salvage therapy is effective for patients with chronic hepatitis B virus infection who have previously failed to respond to lamivudine and adefovir dipivoxil, 5-year TDF-109 study data show.

Treatment with a tenofovir disoproxil fumarate-containing regimen or entecavir leads to high virologic and biochemical response rates in patients with chronic hepatitis B virus infection, shows a registry analysis.

Hepatic steatosis, hepatitis B e antigen seropositivity, and age are independently associated with persistent increases in serum alanine aminotransferase levels in patients with chronic hepatitis B virus infection receiving antiviral therapy, a study shows.

Individual fluctuations in eosinophilic inflammation are associated with asthma control, show data from patients in daily practice.

Researchers have devised and validated a clinical risk score that accurately identifies asthma patients who will have persistently frequent severe exacerbations over the long term.

Stepped increases to optimize treatment improve asthma control, but for many patients optimal control still remains elusive, suggest findings from the real-life COAS study.

Treatment with the anti-tumor necrosis factor α antibody golimumab could improve disease activity in children with polyarticular-course juvenile idiopathic arthritis, researchers report.

Total knee arthroplasty and total hip arthroplasty are cost-effective interventions for the treatment of osteoarthritis, results of a systematic review suggest.

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