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Paediatric endocrinology

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  • Cognitive behavioural therapy can improve glycaemic control in diabetic adolescents

  • Favourable short-term safety profile for cross-sex hormones in transgender adolescents

Pulmonary hypertension

06-03-2017 | Pulmonary hypertension | News | Article

Systemic sclerosis associated with poor survival in CTD-PAH

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

03-03-2017 | Pulmonary hypertension | News | Article

Right atrial strain associated with clinical outcomes in PAH

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

10-02-2017 | Pulmonary hypertension | News | Article

Post-treatment pulmonary arterial compliance best predicts PAH prognosis

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

HBV

05-06-2017 | HBV | News | Article

Support for TDF in patients with HBV-related decompensated cirrhosis

Among patients with hepatitis B virus-related decompensated cirrhosis, first-line tenofovir disoproxil fumarate therapy not only reduces HBV DNA levels, but also improves hepatic function, indicates a real-world South Korean study.

01-06-2017 | HBV | News | Article

Higher rate of anti-HBs disappearance with recombinant versus plasma HBV vaccine

The infant recombinant yeast hepatitis B virus vaccine has long-term efficacy, but the rate of disappearance of protective antibodies against hepatitis B surface antigen is higher than with the plasma-derived vaccine, shows a study of Taiwanese university students.

01-06-2017 | HBV | News | Article

PAGE-B model validated in Asian chronic HBV patients

Korean researchers show that the PAGE-B model for prediction of hepatocellular carcinoma risk has applicability in Asian patients with chronic hepatitis B virus infection treated with entecavir or tenofovir disoproxil fumarate.

Asthma

17-07-2017 | Asthma | News | Article

QoL measure gives the asthma patient’s perspective

Researchers have devised a new measure for assessing the effect of asthma on quality of life from the patient’s perspective.

04-07-2017 | Asthma | News | Article

Considerable health burden for patients with poorly controlled asthma

Study findings show a high prevalence of poorly controlled asthma among patients treated with inhaled corticosteroid and long-acting beta-agonist combination therapy, highlighting poor treatment adherence or an unmet need in current treatment.

04-07-2017 | Asthma | News | Article

Regulatory pathway revealed for ILC2-mediated pulmonary inflammation

Suppression of type 2 innate lymphoid cells by activated plasmacytoid dendritic cells could present a regulatory pathway for pulmonary inflammation, early research suggests.

Rheumatology

21-07-2017 | Rheumatology | News | Article

Predictors of infection risk identified in RA patients treated with tocilizumab

High neutrophil counts, leflunomide treatment, and the absence of anti-citrullinated protein antibodies are associated with increased risk for serious infection among patients with rheumatoid arthritis who are treated with tocilizumab, researchers report.

20-07-2017 | Rheumatology | News | Article

Stopping TNF inhibitor treatment has short-term negative impact for RA patients

Patients with rheumatoid arthritis who stop tumor necrosis factor inhibitor therapy experience worse patient-reported outcomes in the short-term than those who continue treatment, analysis of trial data suggests.

14-07-2017 | Rheumatology | News | Article

Statins could reduce mortality risk in patients with ankylosing spondylitis

Initiation of statin treatment is associated with a “substantially lower risk” for mortality among patients with ankylosing spondylitis, researchers report.

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