Diabetes remains an independent risk factor for hepatocellular carcinoma in patients with chronic hepatitis B virus infection even after hepatitis B surface antigen seroclearance, findings indicate.
Japanese researchers have generated a nationwide estimate of total numbers of hepatitis B virus carriers and treated patients in 2011, comparing it with earlier estimates from 2000.
The noninvasive fibrosis-4 index can further refine the existing favorable clinical profile for hepatocellular carcinoma risk in noncirrhotic patients with chronic hepatitis B virus infection and help identify those with the lowest risk, say researchers.
Repeated exacerbations in patients with severe eosinophilic asthma may be associated with accelerated deterioration of lung function, study findings show.
Researchers have been unable to find a reliable rule for identifying patients who are likely to benefit from continued long-term mepolizumab treatment for severe eosinophilic asthma.
Researchers have found that the group 2 innate lymphoid cell phenotype is more heterogeneous than previously thought, with a surface marker and gene expression profile that is highly dynamic.
Results of a phase IIa trial support further investigation of the selective URAT1 inhibitor verinurad in combination with febuxostat for the treatment of gout.