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Paediatric endocrinology

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Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.

  • Three risk factors for CAH hospitalisation identified

  • Endocrine Society publishes paediatric obesity management guidelines

Pulmonary hypertension

06-03-2017 | Pulmonary hypertension | News | Article

Systemic sclerosis associated with poor survival in CTD-PAH

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

03-03-2017 | Pulmonary hypertension | News | Article

Right atrial strain associated with clinical outcomes in PAH

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

10-02-2017 | Pulmonary hypertension | News | Article

Post-treatment pulmonary arterial compliance best predicts PAH prognosis

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

HBV

04-04-2017 | HBV | News | Article

TDF, entecavir efficacy confirmed in real-world HBV cohort

Treatment with a tenofovir disoproxil fumarate-containing regimen or entecavir leads to high virologic and biochemical response rates in patients with chronic hepatitis B virus infection, shows a registry analysis.

04-04-2017 | HBV | News | Article

Host, viral factors associated with persistently elevated ALT in chronic HBV patients

Hepatic steatosis, hepatitis B e antigen seropositivity, and age are independently associated with persistent increases in serum alanine aminotransferase levels in patients with chronic hepatitis B virus infection receiving antiviral therapy, a study shows.

31-03-2017 | HBV | News | Article

HBV DNA suppression sustained with switch to tenofovir

Italian research shows that patients with chronic hepatitis B virus infection maintain long-term virologic suppression after switching from lamivudine plus adefovir to tenofovir disoproxil fumarate monotherapy, with a low rate of adverse events.

Asthma

18-04-2017 | Asthma | News | Article

Clinical score predicts risk of severe asthma exacerbation trajectory

Researchers have devised and validated a clinical risk score that accurately identifies asthma patients who will have persistently frequent severe exacerbations over the long term.

18-04-2017 | Asthma | News | Article

Many patients fail to achieve good asthma control despite stepped treatment optimization

Stepped increases to optimize treatment improve asthma control, but for many patients optimal control still remains elusive, suggest findings from the real-life COAS study.

18-04-2017 | Asthma | News | Article

Asthma exacerbations reliably predict future risk

A history of asthma exacerbation is a reliable indicator of future risk for exacerbations, say Japanese researchers.

Rheumatology

24-04-2017 | Rheumatology | News | Article

Infection risk with TNF inhibitors confirmed in juvenile idiopathic arthritis

Study results suggest that tumor necrosis factor-alpha inhibitors are associated with a higher risk for serious infection than disease-modifying antirheumatic drugs among children with juvenile idiopathic arthritis.

21-04-2017 | Rheumatology | News | Article

Support for mycophenolate therapy in patients with SSc-related interstitial lung disease

Mycophenolate mofetil is associated with improvements in lung function compared with placebo among patients with systemic sclerosis (SSc)-associated interstitial lung disease, study results suggest.

20-04-2017 | Rheumatology | News | Article

Tocilizumab efficacy maintained for up to 2 years in RA patients

Patients with early rheumatoid arthritis who are treated with tocilizumab maintain the clinical benefits during their second year of treatment, analysis of phase III study data suggests.

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