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Other current therapy areas

Paediatric endocrinology

Interested in paediatric endocrinology?

Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.

  • KIGS data confirm male predominance in treated GH disorders

  • ‘Surgical dogma’ challenged for paediatric well-differentiated thyroid carcinoma

Pulmonary hypertension

10-02-2017 | Pulmonary hypertension | News | Article

Post-treatment pulmonary arterial compliance best predicts PAH prognosis

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

02-02-2017 | Pulmonary hypertension | News | Article

Ambrisentan–tadalafil combination beneficial in CTD-associated PAH

A post-hoc subgroup analysis of the AMBITION trial suggests that the benefits of ambrisentan and tadalafil combination therapy extend to patients with connective tissue disease-associated pulmonary arterial hypertension.

20-01-2017 | Pulmonary hypertension | News | Article

Biological similarities between Cpc-PH and PAH identified

Research published in the Journal of the American College of Cardiology suggests that there could be a pathophysiological overlap between combined post-capillary and pre-capillary pulmonary hypertension and pulmonary arterial hypertension.

HBV

10-02-2017 | HBV | News | Article

Liver fibrosis steadily increases in untreated HBV with stable viral load

Liver fibrosis, estimated using the Fibrosis-4 index, increases significantly over time in untreated patients with hepatitis B infection, despite viral loads remaining largely stable, US researchers report.

09-02-2017 | HBV | News | Article

IFN-λ3 induction shows potential as anti-HBV therapy

Early research from Japan suggests that induction of interferon-λ3 could be a promising therapeutic strategy in patients with hepatitis B virus infection.

09-02-2017 | HBV | News | Article

Albumin–bilirubin score predicts HBV-related cirrhosis survival

Research shows that the albumin–bilirubin score is a significant determinant of the long-term prognosis of patients with hepatitis B virus-associated cirrhosis, outplaying both the Child–Pugh and model for end-stage liver disease scores for this purpose.

Asthma

13-02-2017 | Asthma | News | Article

Eosinophilic airway inflammation and microbiome link

Eosinophilic airway inflammation in patients with asthma is associated with an altered microbiome in the lower airway, report researchers.

13-02-2017 | Asthma | News | Article

Biomarkers aid Type-2 inflammation phenotype selection

Researchers have identified a panel of clinically accessible biomarkers that may help select asthma patients with an airway-mucosal T-helper 2 inflammation phenotype.

13-02-2017 | Asthma | News | Article

Mepolizumab benefits Japanese patients with severe eosinophilic asthma

Mepolizumab is effective for the treatment of severe eosinophilic asthma in Japanese patients, indicates a post-hoc analysis of the phase III MENSA trial.

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