Other current therapy areas

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

The Japanese nationwide selective vaccination strategy has led to a substantial reduction in perinatal hepatitis B virus transmission, say researchers who evaluated the prevalence of hepatitis B surface antigen among pregnant women born before and after its implementation.

A high burden of metabolic risk factors significantly increases the risk for hepatocellular carcinoma among men with hepatitis B virus infection, particularly those who smoke, researchers from Taiwan report.

In patients with persistently low serum levels of hepatitis B virus DNA, the combined use of the noninvasive aspartate aminotransferase to platelet ratio index and the Fibrosis-4 index could help identify those at increased risk for developing hepatocellular carcinoma.

The majority of Japanese patients with severe, difficult-to-treat asthma are likely to present with type 2 asthma and a substantial proportion overlap between two or more subphenotypes, a study suggests.

A European study suggests gene profiles differ in severe asthma that begins in adulthood rather than childhood, indicating distinct underlying mechanisms at work.

Study findings validate a point-of-care device for assessing blood eosinophils that could help in the management of severe asthma.

Baricitinib treatment is associated with greater improvements in patient-reported outcomes than methotrexate monotherapy, suggests an analysis of the RA-BEGIN trial.

Changing sedentary behavior needs to be a focus for patients who undergo total knee or hip joint replacement, US researchers maintain.

Targeting factors such as inflammation and disease activity in patients with rheumatoid arthritis could help reduce their risk for cardiovascular disease, study findings suggest.