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Paediatric endocrinology

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  • Favourable short-term safety profile for cross-sex hormones in transgender adolescents

Pulmonary hypertension

06-03-2017 | Pulmonary hypertension | News | Article

Systemic sclerosis associated with poor survival in CTD-PAH

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

03-03-2017 | Pulmonary hypertension | News | Article

Right atrial strain associated with clinical outcomes in PAH

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

10-02-2017 | Pulmonary hypertension | News | Article

Post-treatment pulmonary arterial compliance best predicts PAH prognosis

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.


22-09-2017 | HBV | News | Article

Perinatal HBV infection ‘nearly eliminated’ with Japan’s selective vaccination program

The Japanese nationwide selective vaccination strategy has led to a substantial reduction in perinatal hepatitis B virus transmission, say researchers who evaluated the prevalence of hepatitis B surface antigen among pregnant women born before and after its implementation.

22-09-2017 | HBV | News | Article

High metabolic risk burden increases HCC risk in HBV patients

A high burden of metabolic risk factors significantly increases the risk for hepatocellular carcinoma among men with hepatitis B virus infection, particularly those who smoke, researchers from Taiwan report.

15-08-2017 | HBV | News | Article

Serum biomarkers combine to improve HCC risk stratification in HBV patients with low viremia

In patients with persistently low serum levels of hepatitis B virus DNA, the combined use of the noninvasive aspartate aminotransferase to platelet ratio index and the Fibrosis-4 index could help identify those at increased risk for developing hepatocellular carcinoma.


04-09-2017 | Asthma | News | Article

Japanese subphenotypes of type 2 severe asthma identified

The majority of Japanese patients with severe, difficult-to-treat asthma are likely to present with type 2 asthma and a substantial proportion overlap between two or more subphenotypes, a study suggests.

04-09-2017 | Asthma | News | Article

Gene profiles differ in adult- and childhood-onset severe asthma

A European study suggests gene profiles differ in severe asthma that begins in adulthood rather than childhood, indicating distinct underlying mechanisms at work.

09-08-2017 | Asthma | News | Article

Point-of-care device shows promise for blood eosinophil count in severe asthma

Study findings validate a point-of-care device for assessing blood eosinophils that could help in the management of severe asthma.


21-09-2017 | Rheumatology | News

Better PROs with baricitinib versus methotrexate

Baricitinib treatment is associated with greater improvements in patient-reported outcomes than methotrexate monotherapy, suggests an analysis of the RA-BEGIN trial.

19-09-2017 | Rheumatology | News | Article

Physical activity promotion needed after total knee or hip replacement

Changing sedentary behavior needs to be a focus for patients who undergo total knee or hip joint replacement, US researchers maintain.

18-09-2017 | Rheumatology | News | Article

RA disease activity and severity play ‘important role’ in reducing CVD risk

Targeting factors such as inflammation and disease activity in patients with rheumatoid arthritis could help reduce their risk for cardiovascular disease, study findings suggest.

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