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Paediatric endocrinology

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Visit our dedicated microsite for research news, interviews and in-depth analysis of paediatric endocrinology and growth disorders.

  • Cognitive behavioural therapy can improve glycaemic control in diabetic adolescents

  • Favourable short-term safety profile for cross-sex hormones in transgender adolescents

Pulmonary hypertension

06-03-2017 | Pulmonary hypertension | News | Article

Systemic sclerosis associated with poor survival in CTD-PAH

A Chinese cohort study identifies factors associated with prognosis among patients with connective tissue disease-associated pulmonary arterial hypertension.

03-03-2017 | Pulmonary hypertension | News | Article

Right atrial strain associated with clinical outcomes in PAH

Study results suggest that right atrial strain could predict adverse outcomes among patients with pulmonary arterial hypertension.

10-02-2017 | Pulmonary hypertension | News | Article

Post-treatment pulmonary arterial compliance best predicts PAH prognosis

Evaluation of pulmonary arterial compliance after initiation or escalation of therapy for pulmonary arterial hypertension more accurately predicts prognosis than conventional right heart hemodynamic parameters, Italian study findings indicate.

HBV

07-04-2017 | HBV | News | Article

Tenofovir-based salvage therapy has long-term benefits in chronic hepatitis B

Long-term tenofovir disoproxil fumarate salvage therapy is effective for patients with chronic hepatitis B virus infection who have previously failed to respond to lamivudine and adefovir dipivoxil, 5-year TDF-109 study data show.

04-04-2017 | HBV | News | Article

TDF, entecavir efficacy confirmed in real-world HBV cohort

Treatment with a tenofovir disoproxil fumarate-containing regimen or entecavir leads to high virologic and biochemical response rates in patients with chronic hepatitis B virus infection, shows a registry analysis.

04-04-2017 | HBV | News | Article

Host, viral factors associated with persistently elevated ALT in chronic HBV patients

Hepatic steatosis, hepatitis B e antigen seropositivity, and age are independently associated with persistent increases in serum alanine aminotransferase levels in patients with chronic hepatitis B virus infection receiving antiviral therapy, a study shows.

Asthma

15-05-2017 | Asthma | News | Article

Sputum eosinophils may help guide asthma control

Individual fluctuations in eosinophilic inflammation are associated with asthma control, show data from patients in daily practice.

18-04-2017 | Asthma | News | Article

Clinical score predicts risk of severe asthma exacerbation trajectory

Researchers have devised and validated a clinical risk score that accurately identifies asthma patients who will have persistently frequent severe exacerbations over the long term.

18-04-2017 | Asthma | News | Article

Many patients fail to achieve good asthma control despite stepped treatment optimization

Stepped increases to optimize treatment improve asthma control, but for many patients optimal control still remains elusive, suggest findings from the real-life COAS study.

Rheumatology

26-05-2017 | Rheumatology | News | Article

Golimumab could be beneficial for children with JIA

Treatment with the anti-tumor necrosis factor α antibody golimumab could improve disease activity in children with polyarticular-course juvenile idiopathic arthritis, researchers report.

25-05-2017 | Rheumatology | News | Article

Surgical interventions for OA may be cost-effective

News in brief

Total knee arthroplasty and total hip arthroplasty are cost-effective interventions for the treatment of osteoarthritis, results of a systematic review suggest.

24-05-2017 | Rheumatology | News | Article

Tocilizumab approved for giant cell arteritis

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