Optometry

Vestibular balance contributes to the risk for falls in individuals with visual impairment, say US researchers.

Clinical trial results point to a role for interleukin-1 targeted agents for the treatment of dry eye disease associated with meibomian gland dysfunction.

A fixed-dose combination of brinzolamide and brimonidine is more effective than either drug given alone for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension, results of a phase III trial indicate.

Macular pigmentation correlates with visual acuity in healthy individuals and people with early age-related macular degeneration, study results indicate.

Rates of surgery for childhood squint in England have fallen dramatically over the past 50 years, shows a study published in the British Journal of Ophthalmology.

Spanish researchers have validated the use of two instruments for determining anterior chamber depth in teenagers and published normative data for the techniques.

Abnormal cholesterol metabolism in the eye is involved in the pathogenesis of age-related macular degeneration, a study in mice has shown.

Conjunctival papillomas that arise in childhood or adolescence tend to be larger, more numerous, and more likely to recur than when they occur in adults, US scientists report.

Toric intraocular lenses offer significant advantages in terms of both vision and quality of life when compared with spherical non-toric lenses, results of a study in patients with corneal astigmatism shows.

Dietary supplementation with a combination of lutein, zeaxanthin, and omega-3 long-chain polyunsaturated fatty acids has a range of potentially beneficial effects in people with age-related macular degeneration, results from a clinical trial have found.

Cytomegalovirus-associated posterior uveitis or panuveitis may occur in patients without evidence of immune insufficiency and is characterized by vitreous inflammation, researchers report.

Aspirin intake is associated with increased risk for early age-related macular degeneration in Asian Indians with cardiovascular disease, a population-based study has found.

Researchers have identified factors that are associated with contact lens wear and care and which predict patients’ compliance with the manufacturers’ recommended replacement frequency.

Functional vision loss is significantly associated with depression, research shows.

Recent study findings indicate that eyes with multifocal intraocular lenses implanted during cataract surgery may develop reduced visual sensitivity.

Researchers are warning against routine antibiotic prophylaxis with intravitreal injection after finding that the practice can increase the antibiotic resistance of ocular surface flora.

Rubbing the eyes leads to an increase in protease activity and levels of protease and inflammatory mediators, a clinical study shows.

Levels of high-sensitivity C-reactive protein predict the risk for age-related macular degeneration and diabetic macular edema, show results of two independent studies published in JAMA Ophthalmology.

Results from a randomized trial suggest that at least three annual mass drug administrations of azithromycin are needed to eliminate trachoma, even in regions with a relatively low initial prevalence of the infection.

The major risk alleles that influence the development of age-related macular degeneration do not predict response to therapy for the condition, a substudy of the CATT trial indicates.