A telephone-delivered, collaborative goal-setting intervention can significantly reduce depressive symptoms relative to usual care in people with uncontrolled diabetes and clinically significant depression, research shows.
Use of a depression treatment program does not improve survival in patients with cancer and comorbid major depression, even though it was highly effective in reducing depressive symptoms, UK researchers report.
Patients with late-life depression have an increased risk of dementia if their symptoms increase over time, whereas a single episode of depression, even if severe, does not carry a significant risk, study findings indicate.
The use of citalopram for the treatment of agitation in Alzheimer’s disease may be limited to a small group of people with moderate agitation and low levels of cognitive impairment, study findings suggest.
Patients at high genetic risk of bipolar disorder may be able to avert onset of the condition due to natural adaptive neuroplasticity that allows the brain to compensate for underlying network dysfunction associated with the condition, researchers report.
Combining lamotrigine with quetiapine improves the treatment of depressive symptoms in patients with bipolar disorder, with the benefits maintained for at least a year, show findings from the CEQUEL trial.