Depressive symptoms are common in adolescents with juvenile idiopathic arthritis and could predict future pain and disability, suggests an analysis of the Childhood Arthritis Prospective Study.
Use of a depression treatment program does not improve survival in patients with cancer and comorbid major depression, even though it was highly effective in reducing depressive symptoms, UK researchers report.
Patients with late-life depression have an increased risk of dementia if their symptoms increase over time, whereas a single episode of depression, even if severe, does not carry a significant risk, study findings indicate.
Research in JAMA Oncology highlights the need for psychological management and support as early during the course of cancer as the initial workup leading to a diagnosis.
The use of citalopram for the treatment of agitation in Alzheimer’s disease may be limited to a small group of people with moderate agitation and low levels of cognitive impairment, study findings suggest.
Patients at high genetic risk of bipolar disorder may be able to avert onset of the condition due to natural adaptive neuroplasticity that allows the brain to compensate for underlying network dysfunction associated with the condition, researchers report.
Combining lamotrigine with quetiapine improves the treatment of depressive symptoms in patients with bipolar disorder, with the benefits maintained for at least a year, show findings from the CEQUEL trial.
A Cochrane review of evidence to date has cast uncertainty over the magnitude of benefit children with attention deficit/hyperactivity gain by taking methylphenidate.
Psychological interventions for adult attention deficit/hyperactivity disorder are best combined with methylphenidate, show findings from the COMPAS trial.
Multiple sclerosis has a nonspecific effect on psychiatric morbidity, increasing the risk of all psychiatric disorders, shows a large population-based study.
Prodromal psychiatric symptoms may be more common in patients with Huntington’s disease than previously thought and worsen as the condition progresses, longitudinal study findings show.
Stable lithium maintenance therapy does not increase the risk of renal dysfunction in patients with bipolar affective disorder, findings from a population-based study suggest.
Study findings show the importance of pharmacological treatment for attention deficit/hyperactivity disorder in ameliorating the increased risk of injuries associated with the condition.
Almost half of patients with bipolar disorder will have comorbid anxiety disorder in their lifetime, show the findings of a systematic review and meta-analysis.
Longitudinal analysis of a birth cohort raises the possibility that attention deficit/hyperactivity disorder in children and in adults may be distinct and unrelated disorders.