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08-04-2019 | Asthma | News | Article

Prevalence of severe eosinophilic asthma estimated in Japan

Approximately one third of patients with severe asthma in Japan have severe eosinophilic asthma, show findings from a cohort analysis.

28-03-2019 | Asthma | News | Article

Greater consideration of small airways dysfunction warranted in asthma management

Small airways dysfunction occurs across all degrees of asthma severity but has the highest prevalence among individuals with the most severe disease, suggest baseline findings from the ATLANTIS study.

21-03-2019 | Respiratory | News | Article

Pirfenidone a ‘feasible treatment option’ for advanced IPF

A post-hoc analysis of the RECAP study suggests that pirfenidone-treated patients with idiopathic pulmonary fibrosis experience similar rates of lung function decline irrespective of whether they have more or less advanced disease.

14-03-2019 | Asthma | News | Article

Chronic cough may point to more severe asthma phenotype

Among patients with asthma, those with chronic cough have worse respiratory symptoms and lung function, and higher levels of some inflammatory markers, than those without, study findings indicate.

07-03-2019 | Respiratory | News | Article

No survival benefit of add-on cyclophosphamide following IPF exacerbation

The addition of intravenous cyclophosphamide to corticosteroid treatment is not associated with significantly improved survival among patients with an acute exacerbation of idiopathic pulmonary fibrosis, researchers report.

28-02-2019 | Respiratory | News | Article

Antifibrinolytic therapy reduces haemoptysis admission in cystic fibrosis

Systemic antifibrinolytic therapy could help to reduce haemoptysis hospital admissions among patients with cystic fibrosis, suggests research.

27-02-2019 | Asthma | News | Article

Support for MET and MMP10 roles in eosinophilic asthma

MET and MMP10 gene expression are likely to play important roles in the cellular inflammation and airway remodeling associated with submucosal eosinophilia in patients with asthma, researchers report.

21-02-2019 | Respiratory | News | Article

Asthma remains a ‘significant healthcare burden’

An analysis of electronic primary care records indicates that the prevalence of asthma continues to be high in the UK, with an increasing proportion of patients treated with inhaled corticosteroids.

14-02-2019 | Respiratory | News | Article

Sustained benefits of pirfenidone demonstrated in IPF patients

Findings from a Czech registry study suggest that pirfenidone treatment is associated with a lasting reduction in lung function decline and mortality risk among patients with idiopathic pulmonary fibrosis.

07-02-2019 | Asthma | News | Article

No benefit of antibiotic treatment for hospitalised asthma patients

Findings from a large US study suggest that early treatment with antibiotics is not associated with improved outcomes among patients hospitalised for asthma exacerbation and treated with systemic corticosteroids.

31-01-2019 | Respiratory | News | Article

Lumacaftor–ivacaftor combination shows promise in young children with cystic fibrosis

Trial findings published in The Lancet Respiratory Medicine support the use of combination therapy with lumacaftor and ivacaftor in children aged 2–5 years with cystic fibrosis homozygous for the F508del-CFTR mutation.

24-01-2019 | Respiratory | News | Article

Breath biomarkers could aid IPF detection

A number of exhaled biomarkers have the potential to discriminate between patients with idiopathic pulmonary fibrosis and healthy controls, but further work is needed to confirm their clinical utility, say the authors of a systematic review.

17-01-2019 | Asthma | News | Article

Better adherence with once- than twice-daily ICS/LABA therapy in asthma patients

Patients with asthma who are treated with the once-daily inhaled corticosteroid/long-acting beta agonist regimen fluticasone furoate/vilanterol have better treatment adherence than those taking the twice-daily budesonide/formoterol combination, researchers report.

14-01-2019 | Asthma | News | Article

Most patients with asthma will not experience an exacerbation

Only a third of patients with asthma will experience an exacerbation, show 7 years of observation in more than 50,000 adults with the condition.

10-01-2019 | Respiratory | News | Article

Further investigation of omeprazole warranted in patients with IPF

The proton pump inhibitor omeprazole is well tolerated and may reduce cough frequency in patients with idiopathic pulmonary fibrosis, suggest results from a pilot phase II trial.

20-12-2018 | Asthma | News | Article

Genetic variants linked to moderate-to-severe asthma susceptibility

A genome-wide association study has identified novel genetic variants associated with the risk of developing moderate-to-severe asthma, a substantial proportion of which are also associated with mild asthma susceptibility.

18-12-2018 | Asthma | News | Article

Blood eosinophil variability has treatment decision effects

Researchers have highlighted the need for blood eosinophils to be repeatedly measured in patients with severe asthma when designating treatment having found that levels vary in individuals over time.

13-12-2018 | Respiratory | News | Article

Slow gait speed predicts poor prognosis in patients with IPF

Study findings suggest that slow gait speed is significantly associated with an increased risk of mortality and hospitalisation among patients with idiopathic pulmonary fibrosis .

06-12-2018 | Asthma | News | Article

Tralokinumab does not reduce corticosteroid use in patients with severe asthma

Findings from the TROPOS trial indicate that treatment with the interleukin-13-targeted monoclonal antibody tralokinumab does not decrease corticosteroid use among patients with severe uncontrolled asthma.

29-11-2018 | Respiratory | News | Article

Support for continued pirfenidone treatment in patients with IPF progression

Patients with idiopathic pulmonary fibrosis who have previously experienced disease progression whilst receiving pirfenidone may benefit from continued treatment with the antifibrotic agent, researchers report.

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