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10-03-2013 | Immunology | Article

Shingles risk in rheumatoid arthritis independent of biologics

Choosing between biologic and nonbiologic treatment pathways does not alter the risk for shingles in patients with rheumatoid arthritis and other autoimmune conditions, suggest results from a large cohort study published in JAMA.

07-03-2013 | Internal medicine | Article

Experience shows in febrile neutropenia treatment

The strongest predictors of guideline-compliant care of cancer patients with febrile neutropenia are the case volumes of the treating physicians and hospitals, a study shows.

06-03-2013 | Immunology | Article

Salty diet may trigger autoimmune disease

Results from two studies published in Nature show that eating a salty diet may trigger the development of autoimmunity.

05-03-2013 | Immunology | Article

Pain self-management and exercise ‘effective in elderly’

Techniques for the self-management of chronic pain based on cognitive behavioral therapy significantly reduce disability, suggest results from a randomized controlled trial in older adults.

04-03-2013 | Genetics | Article

Gene cluster implicated in Behçet's disease

Scientists may have uncovered an underlying genetic susceptibility for Behçet's disease in East Asian patients.

03-03-2013 | Gynaecology | Article

Forceps delivery ‘does not increase atopy risk’

Results from a population-based cohort study suggest that forceps-assisted birth is associated with an increased risk for asthma, but not allergic sensitization, in later childhood.

03-03-2013 | Immunology | Article

Omalizumab scratches the itch for urticaria patients

The monoclonal antibody omalizumab seems to be effective at relieving symptoms for patients with chronic idiopathic urticaria who have not responded to H1-antihistamine therapy, report US researchers.

25-02-2013 | Immunology | Article

Natalizumab may be second-line option for pediatric MS patients

Natalizumab may be an effective and well tolerated second-line treatment for pediatric patients with highly active relapsing-remitting multiple sclerosis, say researchers.

24-02-2013 | Immunology | Article

Kaposi’s sarcoma risk factors revealed

Scientists have uncovered an intriguing relationship between the risk for Kaposi’s sarcoma, smoking, and the use of highly active antiretroviral therapy.

24-02-2013 | Cardiology | Article

Protamine–heparin complex antibodies raise concerns

Almost a third of patients treated with protamine for heparin reversal during cardiopulmonary bypass develop antibodies to circulating protamine–heparin complexes, study findings suggest.

24-02-2013 | Psychology | Article

Mental health risk increased in children with atopic dermatitis

Results from a US study suggest that children with atopic dermatitis (AD) are at significantly increased risk for mental health disorders.

20-02-2013 | Immunology | Article

Exhaled nitric oxide shows promise as childhood asthma predictor

High levels of exhaled nitric oxide in infancy predict asthma development in later childhood, show study findings.

19-02-2013 | Immunology | Article

Growth in opioid use prompts safety concerns

Prescriptions for opioid drugs have increased significantly in Germany over the past decade, a survey of insurance data has found.

18-02-2013 | Immunology | Article

Severe childhood asthma blood test hopes dashed

Blood eosinophil counts do not reliably reflect airway eosinophil concentrations in children with severe, therapy-resistant asthma, and therefore cannot be used to make therapeutic decisions, researchers report.

17-02-2013 | Gastroenterology | Article

Early PBC prognosis advocated

Biochemical response to ursodeoxycholic acid at 6 months is a better predictor for primary biliary cirrhosis prognosis than the current standard of 1 year, study results suggest.

17-02-2013 | Immunology | Article

Eosinophilic inflammation of the esophagus relieved by diet

A diet that eliminates six food types has proved effective at inducing remission of eosinophilic esophagitis in adults, report researchers.

17-02-2013 | Immunology | Article

Antibody test ‘inappropriate’ without connective tissue symptoms

The positive antinuclear antibody test is often used inappropriately in patients without indications of connective tissue disease, real-world research suggests.

17-02-2013 | Immunology | Article

Age not a major factor in asthma allergic sensitization rates

Results from a US study suggest that there is no significant difference in allergic sensitization rates between younger and older patients with asthma.

13-02-2013 | Gastroenterology | Article

Elemental diet may help adults with eosinophilic esophagitis

Results from a small study suggest that consumption of an elemental diet for 2–4 weeks results in a significant histologic improvement in adult patients with eosinophilic esophagitis.

12-02-2013 | Immunology | Article

Xpert diagnosis of TB and its drug resistant strains

The use of a novel, diagnostic test called Xpert is both sensitive and specific in detecting tuberculosis and rifampicin resistance, report US researchers.