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04-03-2019 | Oncology | News | Article

Vitiligo may protect against internal malignancy

Patients with the autoimmune disorder vitiligo have a “markedly reduced” risk for developing malignancies of internal organs compared with other individuals, Korean researchers report.

20-12-2018 | Oncology | Main feed | News

Hematologic immune-related adverse events with immune checkpoint inhibition are rare but serious

Hematologic immune-related adverse events are rare but potentially life-threatening complications of anti-PD-1 or anti-PD-L1 immunotherapy, according to a large observational study.

09-03-2016 | Pulmonary hypertension | News | Article

Regulatory immune cells compromised in PAH

Research suggests that regulatory T cells may play a part in all subtypes of pulmonary arterial hypertension.

18-08-2013 | Rheumatology | Article

Periodontitis may induce rheumatoid arthritis precursor

Periodontal disease caused by Porphyromonas gingivalis infection can induce the autoimmune response that characterizes rheumatoid arthritis, a pilot study indicates.

12-08-2013 | Respiratory | Article

Asthma–food allergy combination linked to poor outcomes

US research in a group of inner-city school children with asthma shows that those with food allergies experience greater asthma-related morbidity, use more healthcare resources, and have greater lung function impairment than those without.

11-08-2013 | Infectious disease | Article

Atopic disease, IgE antibodies increase risk for adult RTI

Study data from Finland confirm that atopic disease increases the risk for both lower and upper respiratory tract infection in working-age adults.

11-08-2013 | Rheumatology | Article

Rituximab shows long-term efficacy in antibody-associated vasculitis

A single course of rituximab is a viable alternative to conventional cyclophosphamide/azathioprine immunosuppression in patients with severe antineutrophil cytoplasmic antibody-associated vasculitis, long-term results of the RAVE trial suggests.

08-08-2013 | Respiratory | Article

COPD, asthma linked to poor anaphylaxis outcomes

Researchers have found that patients with chronic lung diseases, including asthma and chronic obstructive pulmonary disease, are significantly more likely to have poor outcomes when hospitalized for anaphylaxis and other allergic conditions compared with other patients.

09-06-2013 | Rheumatology | Article

Lupus diagnosis warns of postoperative risks

Patients with systemic lupus erythematosus are at high risk for a poor outcome from surgery, highlights research published in the Annals of Rheumatic Disease.

27-05-2013 | Immunology | Article

New Samter’s syndrome classification proposed

Turkish researchers have developed a classification system for patients with hypersensitivity to non-steroidal anti-inflammatory drugs.

28-04-2013 | Immunology | Article

Overweight exacerbates air pollution symptoms in childhood asthma

Children with asthma who are overweight are more likely to experience symptoms after exposure to indoor air pollution than normal-weight asthmatic children, show study findings.

22-04-2013 | Genetics | Article

Gene responsible for half asplenia cases discovered

Researchers have discovered that mutations in the ribosomal protein SA gene are responsible for around half of all cases of isolated congenital asplenia.

22-04-2013 | Immunology | Article

Single allergen sensitization tests may miss cases in children

There is significant discordance between the results of allergen-specific skin prick tests and allergen-specific serum immunoglobulin E levels for identifying aeroallergen sensitization in children under the age of 4 years, a study finds.

21-04-2013 | Metabolism | Article

Monoclonal antibody single therapy not effective in Type 1 diabetes

The monoclonal antibodies canakinumab and anakinra, inhibitors of the innate immune mediator interleukin-1β, do not seem to be effective at slowing the decline of β-cell function in individuals with recent-onset Type 1 diabetes, report researchers.

21-04-2013 | Metabolism | Article

Sjögren’s syndrome found in one-fifth of lupus patients

Researchers have identified key characteristics that predict the development of Sjögren’s syndrome in patients with systemic lupus erythematosus, finding that up to a fifth of patients are affected.

15-04-2013 | Immunology | Article

CD8 cell subset count linked to airway obstruction in asthma

The frequency of a subset of CD8 T lymphocytes expressing the high-affinity receptor for LTB4 and producing interleukin-13 is significantly greater in the airways of patients with asthma than healthy people, a study finds.

14-04-2013 | Immunology | Article

Combination therapy shows promise for relapsing MS

Combining the two most common therapies for relapsing-remitting multiple sclerosis provides improved reduction of new lesion activity and accumulation of total lesion over either single-agents, show findings from a randomized, placebo-controlled trial.

10-04-2013 | Immunology | Article

GPs request unnecessary RF tests

General practitioners may be requesting inappropriate tests for rheumatoid factor, and inflating the costs associated with diagnosis of rheumatoid arthritis, say UK researchers.

08-04-2013 | Immunology | Article

Etanercept reaps workplace benefits

The cost of treatment with the tumor necrosis factor inhibitor etanercept is offset by increased ability to work, suggests a study of US patients with moderate-to-severe rheumatoid arthritis.

07-04-2013 | Internal medicine | Article

IL-2 therapy restores immune tolerancein graft-versus-host disease

Daily administration of interleukin-2 can restore the homeostasis of CD4+Foxp3+ regulatory T cells and promote immune tolerance in patients with graft-versus-host disease, report researchers.