US research in a group of inner-city school children with asthma shows that those with food allergies experience greater asthma-related morbidity, use more healthcare resources, and have greater lung function impairment than those without.
A single course of rituximab is a viable alternative to conventional cyclophosphamide/azathioprine immunosuppression in patients with severe antineutrophil cytoplasmic antibody-associated vasculitis, long-term results of the RAVE trial suggests.
Researchers have found that patients with chronic lung diseases, including asthma and chronic obstructive pulmonary disease, are significantly more likely to have poor outcomes when hospitalized for anaphylaxis and other allergic conditions compared with other patients.
There is significant discordance between the results of allergen-specific skin prick tests and allergen-specific serum immunoglobulin E levels for identifying aeroallergen sensitization in children under the age of 4 years, a study finds.
The monoclonal antibodies canakinumab and anakinra, inhibitors of the innate immune mediator interleukin-1β, do not seem to be effective at slowing the decline of β-cell function in individuals with recent-onset Type 1 diabetes, report researchers.
The frequency of a subset of CD8 T lymphocytes expressing the high-affinity receptor for LTB4 and producing interleukin-13 is significantly greater in the airways of patients with asthma than healthy people, a study finds.
Combining the two most common therapies for relapsing-remitting multiple sclerosis provides improved reduction of new lesion activity and accumulation of total lesion over either single-agents, show findings from a randomized, placebo-controlled trial.