Patients with newly diagnosed pulmonary arterial hypertension have a substantial burden of disease, with more than half hospitalised during the first 3 years post-diagnosis, research shows.
An updated CHEST guideline for treating pulmonary arterial hypertension provides some evidence-based recommendations but also highlights many evidence gaps.
Oxygen uptake efficiency plateau, measured during the cardiopulmonary exercise test, offers a novel method for evaluating gas exchange abnormalities in patients with idiopathic pulmonary hypertension, Chinese researchers report.
Measuring night-time variability in the blood pressure of patients with hypertension may help to predict their risk of having a cardiovascular event, show data from an international study.
Exercise haemodynamic variables, measured shortly after diagnosis, correlate with exercise capacity and predict survival in patients with pulmonary arterial hypertension, study findings indicate.
The use of and outcomes with ambrisentan in clinical practice are different to those in clinical trials, reflecting different patient characteristics in the “real world”, say researchers.
The associations between blood pressure and cardiovascular disease are variable, reveals a large study that highlights the impact of angina and heart failure.
The systolic blood pressure of elderly people should be kept below 140 mmHg, say researchers who dispute the eighth Joint National Committee guidelines.
N-terminal pro-brain natriuretic peptide remains a valid predictor in patients with pulmonary arterial hypertension who have concomitant renal dysfunction, say researchers.
Researchers have published a protocol for use of inotropic agents during initiation of epoprostenol therapy in patients with severe pulmonary arterial hypertension.
Researchers have identified clinical features that could help predict which patients with systemic sclerosis are likely to go on to develop pulmonary arterial hypertension (PAH) and therefore benefit most from early treatment.