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14-11-2010 | Gynaecology | Article

Exercise may reduce risk for endometrial cancer


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MedWire News: Moderate to vigorous exercise taken for 150 minutes per week could reduce the risk for endometrial cancer, regardless of weight, show US study findings.

"We did see an association between physical activity and endometrial cancer, regardless of BMI [body mass index]," said Hannah Arem from Yale University in New Haven, Connecticut.

"We know that two-thirds of the population in the US are overweight and nearly one third are obese, and we know that this is a risk factor for endometrial cancer," she added.

Arem and colleagues age-matched 668 women with endometrial cancer with 665 healthy women and collected demographic information concerning environmental and lifestyle exposures.

They found that women of normal weight (BMI <25 kg/m2) who exercised for 150 minutes per week had a 73% reduced risk for endometrial cancer compared with inactive and overweight (BMI ≥25 kg/m2) women.

Furthermore, women who reported 7.5 metabolic equivalent (MET) hours (150 minutes) per week of moderate-vigorous exercise (including fast-paced walking) had a 34 percent lower risk for endometrial cancer than women who reported no MET hours per week, even after adjustment for risk factors including BMI.

"We think this is an important public health message for women who are at risk for endometrial cancer," concluded Arem.

MedWire ( is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Sarah Guy

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