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01-08-2010 | Gynaecology | Article

Mild endometriosis: similar pregnancy rates to healthy women


Journal abstract

MedWire News: Women with mild endometriosis (stage I disease) can expect to achieve similar pregnancy rates as women without endometriosis, show the results of an artificial insemination (AI) donor study.

"A great controversy exists about the association between minimal endometriosis and symptoms, especially as regards fertility," write Roberto Matorras, from the Basque Country University in Spain, and co-authors.

Thus, the team compared pregnancy rates between 104 women with stage I endometriosis and 196 women without, who underwent donor AI as a result of having azoospermic partners.

The per-cycle and per-woman pregnancy rates were slightly, but not statistically different among the women, at a respective 8.6 percent and 13.3 percent, and 37.5 percent and 51.0 percent, for women with endometriosis and those without.

The cumulative pregnancy rate after six AI cycles in women with endometriosis was similar to that after three cycles in women without the disease, observe the researchers.

Matorras et al conclude that although they observed a trend toward lower pregnancy rates in women with minimal endometriosis, the reduction was considerably lower than was previously suggested.

MedWire ( is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Sarah Guy