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31-01-2010 | Gynaecology | Article

Hysteroscopic septal resection improves obstetric outcome

Abstract

Journal abstract

MedWire News: Women with infertility, a history of recurrent miscarriage, or preterm delivery show significantly improved obstetric outcomes with hysteroscopic septal resection, show researchers.

Congenital uterine anomalies resulting from mullerian fusion defects are the most common types of reproductive system malformations, with the septate uterus occurring most frequently. With the advent of new surgical techniques, septal resection is now a brief endoscopic daycare procedure with low morbidity and quick recovery.

K Roy (All India Institute of Medical Sciences, New Dehli) and colleagues therefore investigated the efficacy of hysteroscopic septal resection by monopolar electrode knife in a cohort of 170 women (mean age = 25.6 years) with confirmed uterine septa and recurrent miscarriages (68.2 percent), infertility (17.6 percent), or preterm deliveries (14.1 percent).

After a mean follow-up of 28.5 months, the team looked at pre- and post-surgery data and found a significant reduction in the number of miscarriages (91.5 vs 12.9 percent) and increases in the number of term deliveries (2.5 vs 79.5 percent). However, the number of preterm deliveries remained similar, at 6.1 versus 7.5 percent.

Furthermore, 13 (56.5 percent) of 23 infertile patients conceived after septal resection, and the take-home baby rate increased from 8.5 percent pre-surgery to 87.1 percent post-surgery. In total, 51.2 percent of women had their first live birth within 10-15 months.

Roy and team conclude that hysteroscopic septal resection is “a safe and effective method of choice for improving obstetric outcome” in these women.

MedWire (www.medwire-news.md) is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010

By Ingrid Grasmo